Table 2.

Association between CECs at 2 months and response to therapy




CECs at 2 mo


No. patients
11/μL or less, no. (%)
More than 11/μL, no. (%)
P
Global response     
    Complete response   5   1 (2.3)   4 (10.8)   
    Partial response   13   6 (13.6)   7 (18.9)   
    Stable disease   32   16 (36.4)   16 (43.2)   
    Progressive disease   31   21 (47.7)   10 (27.0)   .03*  
    CR + PR   18   7 (15.9)   11 (29.7)   
    SD + PD   63   37 (84.1)   26 (70.3)   .18  
    CR + PR + SD   50   23 (52.3)   27 (73.0)   
    PD   31   21 (47.7)   10 (27.0)   .07  
Clinical benefit     
    SD > 24 wk + PR + CR   37   13 (29.6)   24 (64.9)   
    SD < 24 wk + PD   44   31 (70.4)   13 (35.1)   .002*  
Response at 2 mo     
    Response   30   14 (34.2)   16 (48.5)   
    Stable disease   22   12 (29.3)   10 (30.3)   
    Progression
 
22
 
15 (36.6)
 
7 (21.2)
 
.13
 



CECs at 2 mo


No. patients
11/μL or less, no. (%)
More than 11/μL, no. (%)
P
Global response     
    Complete response   5   1 (2.3)   4 (10.8)   
    Partial response   13   6 (13.6)   7 (18.9)   
    Stable disease   32   16 (36.4)   16 (43.2)   
    Progressive disease   31   21 (47.7)   10 (27.0)   .03*  
    CR + PR   18   7 (15.9)   11 (29.7)   
    SD + PD   63   37 (84.1)   26 (70.3)   .18  
    CR + PR + SD   50   23 (52.3)   27 (73.0)   
    PD   31   21 (47.7)   10 (27.0)   .07  
Clinical benefit     
    SD > 24 wk + PR + CR   37   13 (29.6)   24 (64.9)   
    SD < 24 wk + PD   44   31 (70.4)   13 (35.1)   .002*  
Response at 2 mo     
    Response   30   14 (34.2)   16 (48.5)   
    Stable disease   22   12 (29.3)   10 (30.3)   
    Progression
 
22
 
15 (36.6)
 
7 (21.2)
 
.13
 
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