Increased thymocyte proliferation in healthy young VavP-MYC mice
. | 2 weeks old . | . | . | . | 6 weeks old . | . | . | . | . | . | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| . | Wild-type; n = 4 . | . | MYC17; n = 2 . | . | Wild-type; n = 5 . | . | MYC10; n = 5 . | . | MYC10hom; n = 5 . | . | ||||||||
. | S phase . | G2/M phase . | S phase . | G2/M phase . | S phase . | G2/M phase . | S phase . | G2/M phase . | S phase . | G2/M phase . | ||||||||
| CD4+ CD8+* | 11.6 ± 0.7 | 0.8 ± 0.1 | 15.9 ± 0.6 | 1.4 ± 0.2 | 7.6 ± 1 | 1.6 ± 0.3 | 9.2 ± 0.3 | 1.7 ± 0.3 | 10.3 ± 0.6 | 1.9 ± 0.4 | ||||||||
| P | — | — | .01 | .01 | — | — | .01 | > .05 | .001 | > .05 | ||||||||
| CD4+ CD8-* | 9.7 ± 0.4 | 0.8 ± 0.1 | 28.8 ± 0.8 | 1.3 ± 0.4 | 3.1 ± 0.9 | 1.1 ± 0.2 | 7.1 ± 0.2 | 1.3 ± 0.2 | 15.0 ± 0.5 | 1.5 ± 0.2 | ||||||||
| P | — | — | < .001 | > .05 | — | — | .001 | > .05 | < .001 | > .05 | ||||||||
| CD4- CD8+* | 40.1 ± 1.6 | 0.9 ± 0.3 | 37.6 ± 0.5 | 0.8 ± 0.1 | 14.7 ± 2.4 | 1.3 ± 0.3 | 21.9 ± 1.2 | 1.5 ± 0.3 | 26.7 ± 1.1 | 1.6 ± 0.4 | ||||||||
| P | — | — | > .05 | > .05 | — | — | .01 | > .05 | < .001 | > .05 | ||||||||
. | 2 weeks old . | . | . | . | 6 weeks old . | . | . | . | . | . | ||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| . | Wild-type; n = 4 . | . | MYC17; n = 2 . | . | Wild-type; n = 5 . | . | MYC10; n = 5 . | . | MYC10hom; n = 5 . | . | ||||||||
. | S phase . | G2/M phase . | S phase . | G2/M phase . | S phase . | G2/M phase . | S phase . | G2/M phase . | S phase . | G2/M phase . | ||||||||
| CD4+ CD8+* | 11.6 ± 0.7 | 0.8 ± 0.1 | 15.9 ± 0.6 | 1.4 ± 0.2 | 7.6 ± 1 | 1.6 ± 0.3 | 9.2 ± 0.3 | 1.7 ± 0.3 | 10.3 ± 0.6 | 1.9 ± 0.4 | ||||||||
| P | — | — | .01 | .01 | — | — | .01 | > .05 | .001 | > .05 | ||||||||
| CD4+ CD8-* | 9.7 ± 0.4 | 0.8 ± 0.1 | 28.8 ± 0.8 | 1.3 ± 0.4 | 3.1 ± 0.9 | 1.1 ± 0.2 | 7.1 ± 0.2 | 1.3 ± 0.2 | 15.0 ± 0.5 | 1.5 ± 0.2 | ||||||||
| P | — | — | < .001 | > .05 | — | — | .001 | > .05 | < .001 | > .05 | ||||||||
| CD4- CD8+* | 40.1 ± 1.6 | 0.9 ± 0.3 | 37.6 ± 0.5 | 0.8 ± 0.1 | 14.7 ± 2.4 | 1.3 ± 0.3 | 21.9 ± 1.2 | 1.5 ± 0.3 | 26.7 ± 1.1 | 1.6 ± 0.4 | ||||||||
| P | — | — | > .05 | > .05 | — | — | .01 | > .05 | < .001 | > .05 | ||||||||
P indicates P value calculated by t test; —, not applicable.
Values in these rows are expressed as % ± SEM.