Table 4. The effect of 0157LPS on... | American Society of Hematology

Table 4.

The effect of 0157LPS on platelet counts in mice

Strain	Median platelet counts without LPS, × 10⁹/L^*(range)	Median platelet counts with LPS, × 10⁹/L (range)	P
C57BL/10ScSn	950 (830-1080)	140 (50-270)†	.001
C57BL/10ScN	700 (640-730)	680 (600-720)‡	—
C3H/HeN	1121 (1065-1340)	525 (495-550)§	.001
C3H/HeJ	1100 (950-1270)	1160 (980-1220)§	—

Strain	Median platelet counts without LPS, × 10⁹/L^*(range)	Median platelet counts with LPS, × 10⁹/L (range)	P
C57BL/10ScSn	950 (830-1080)	140 (50-270)†	.001
C57BL/10ScN	700 (640-730)	680 (600-720)‡	—
C3H/HeN	1121 (1065-1340)	525 (495-550)§	.001
C3H/HeJ	1100 (950-1270)	1160 (980-1220)§	—

Intraperitoneal injection of mice with O157LPS reduced platelet counts in C57BL/10ScSN and C3H/HeN mice compared with mutated mice and with mice given injections of PBS.

—indicates not applicable.

n = 3 mice.

†

n = 9 mice.

‡

n = 8 mice.

n = 6 mice.

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