Table 1. Intensity of CD25 and CD69... | American Society of Hematology

Table 1.

Intensity of CD25 and CD69 expression assessed as mean fluorescence channel (MFC) among activated T lymphocytes

	% CD3⁺CD25⁺ cells remaining	CD25 MFC among remaining activated T cells	CD69 MFC among remaining activated T cells
PHA-stimulated samples
0 nM bortezomib	90	971	207
10 nM bortezomib	82	929	230
100 nM bortezomib	73*	771*	200
1000 nM bortezomib	69*	642*	174*
αCD3/αCD28-stimulated samples
0 nM bortezomib	64	555	276
10 nM bortezomib	56	433	256
100 nM bortezomib	34*	208*	201
1000 nM bortezomib	5*	85*	166*

	% CD3⁺CD25⁺ cells remaining	CD25 MFC among remaining activated T cells	CD69 MFC among remaining activated T cells
PHA-stimulated samples
0 nM bortezomib	90	971	207
10 nM bortezomib	82	929	230
100 nM bortezomib	73*	771*	200
1000 nM bortezomib	69*	642*	174*
αCD3/αCD28-stimulated samples
0 nM bortezomib	64	555	276
10 nM bortezomib	56	433	256
100 nM bortezomib	34*	208*	201
1000 nM bortezomib	5*	85*	166*

P < .05 compared with the respective value of the samples without bortezomib.