Table 1. Results: clonality, JAK2... | American Society of Hematology

Table 1.

Results: clonality, JAK2 mutation, and CD34⁺ cells in peripheral blood

	CD34 %*			JAK2 mutation
Group	No.	Mean (95% CI)*	No.	Mutated (%)	Homozygous (%)	No.	Clonal†
Myelofibrosis with myeloid metaplasia	25	1.1 (0.58-1.64)	23	17 (74)	6 (26)	14	14
Myelofibrosis secondary to PH	19	0.08 (0.04-0.12)	19	0	0	16	1
PV/ET without significant myelofibrosis	6	0.06 (0.02-0.10)	5	4 (80)	0	4	4
Healthy controls	23	0.05 (0.03-0.06)	—	—	—	—	—

	CD34 %*			JAK2 mutation
Group	No.	Mean (95% CI)*	No.	Mutated (%)	Homozygous (%)	No.	Clonal†
Myelofibrosis with myeloid metaplasia	25	1.1 (0.58-1.64)	23	17 (74)	6 (26)	14	14
Myelofibrosis secondary to PH	19	0.08 (0.04-0.12)	19	0	0	16	1
PV/ET without significant myelofibrosis	6	0.06 (0.02-0.10)	5	4 (80)	0	4	4
Healthy controls	23	0.05 (0.03-0.06)	—	—	—	—	—

CD34⁺ cells expressed as a percentage of peripheral-blood white cells.

Denominator only includes female patients with informative X-chromosome exonic polymorphisms; this can be studied only in females.