Table 1.

Results of induction therapy


Patients

No. patients

CR, no. (%, 95% CI)

Median time to CR, d (range)
All   44   39 (89, 75-96)   28 (19-48)  
Low risk   25   24 (96, 80-100)   28 (19-48)  
High risk
 
19
 
15* (79, 54-94)
 
32 (22-41)
 

Patients

No. patients

CR, no. (%, 95% CI)

Median time to CR, d (range)
All   44   39 (89, 75-96)   28 (19-48)  
Low risk   25   24 (96, 80-100)   28 (19-48)  
High risk
 
19
 
15* (79, 54-94)
 
32 (22-41)
 

Low risk was defined as having an initial WBC count below 10 × 109/L; high risk, as having an initial WBC count above 10 × 109/L. The low-risk patient who failed did so within 2 days of the start of therapy; the 4 high-risk patients, within 2, 2, 3, and 17 days of therapy.

*

Eleven of 15 patients with GO, 2 of 2 patients with GO + idarubicin, 1 of 1 patient with idarubicin, and 1 of 1 patient with only ATRA + ATO.

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