Cell fate classification of separated offspring of initially deposited colony-initiating CD34+CD38- cells
. | DC no. 1 . | . | . | . | . | ||||
---|---|---|---|---|---|---|---|---|---|
DC no. 2 . | ML-ICs . | LTC-ICs . | M-NK-ICs . | NK-ICs . | CFUs-M . | ||||
ML-ICs | 2 | — | — | — | — | ||||
LTC-ICs | 3 | 2 | — | — | — | ||||
M-NK-ICs | 6 | 0 | 11 | 0 | — | ||||
NK-ICs | 1 | 1 | 0 | 7 | — | ||||
CFUs-M | 2 | 0 | 8 | 0 | 13 | ||||
Dead | 1 | 0 | 5 | 10 | 4 | ||||
Identical cell fate, no. (%) | 2 (13.3) | 2 (66.7) | 11 (45.8) | 7 (41.2) | 13 (76.5) | ||||
Different cell fate, no. (%) | 13 (86.7) | 1 (33.3) | 13 (54.2) | 10 (58.8) | 4 (23.5) |
. | DC no. 1 . | . | . | . | . | ||||
---|---|---|---|---|---|---|---|---|---|
DC no. 2 . | ML-ICs . | LTC-ICs . | M-NK-ICs . | NK-ICs . | CFUs-M . | ||||
ML-ICs | 2 | — | — | — | — | ||||
LTC-ICs | 3 | 2 | — | — | — | ||||
M-NK-ICs | 6 | 0 | 11 | 0 | — | ||||
NK-ICs | 1 | 1 | 0 | 7 | — | ||||
CFUs-M | 2 | 0 | 8 | 0 | 13 | ||||
Dead | 1 | 0 | 5 | 10 | 4 | ||||
Identical cell fate, no. (%) | 2 (13.3) | 2 (66.7) | 11 (45.8) | 7 (41.2) | 13 (76.5) | ||||
Different cell fate, no. (%) | 13 (86.7) | 1 (33.3) | 13 (54.2) | 10 (58.8) | 4 (23.5) |
The more primitive separated daughter cell is defined as DC no. 1, the other as DC no. 2. Values in table are total numbers of cells except where indicated.
— indicates not applicable.