Table 2.

VZV disease in the 2 study groups


VZV

Acyclovir, no. (%)

Placebo, no. (%)

HR

95% CI

P
By year 1*  2 (5)   10 (26)   0.16   0.035, 0.74   .006  
By year 2   8 (21)   12 (31)   0.52   0.21, 1.3   .15  
By year 3   11 (29)   13 (33)   0.65   0.29, 1.5   .30  
By year 5
 
14 (37)
 
14 (36)
 
0.76
 
0.36, 1.6
 
.46
 

VZV

Acyclovir, no. (%)

Placebo, no. (%)

HR

95% CI

P
By year 1*  2 (5)   10 (26)   0.16   0.035, 0.74   .006  
By year 2   8 (21)   12 (31)   0.52   0.21, 1.3   .15  
By year 3   11 (29)   13 (33)   0.65   0.29, 1.5   .30  
By year 5
 
14 (37)
 
14 (36)
 
0.76
 
0.36, 1.6
 
.46
 

Shown are results from the intent-to-treat analysis and among patients who received at least 30 days of study drug.

HR indicates hazard ratio; CI, confidence interval.

*

Year refers to year after transplantation

One additional case occurred in each group between 6 and 10 years after transplantation

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