Table 2. Percentage of T-cell subsets in... | American Society of Hematology

Table 2.

Percentage of T-cell subsets in peripheral blood from healthy controls, patients without GvHD, and patients with acute intestinal GvHD

		No GvHD			Acute GvHD
Cell type	Healthy ctrls, % of total lymphocytes	% of total lymphocytes	P vs healthy ctrls	% of total lymphocytes	P vs healthy ctrls	P vs no GvHD
CD4⁺/CD3⁺	57.4 ± 4.6	49.3 ± 6.8	NS	42.9 ± 5.5	NS	NS
CD8⁺/CD3⁺	37.2 ± 2.7	38.9 ± 5.3	NS	55.4 ± 4.2	<.01	<.05
CD4⁺CD25^high/CD3⁺	1.0 ± 0.1	2.8 ± 0.6	<.01	0.8 ± 0.2	NS	<.001
CD4⁺CD25^high/CD4⁺	2.3 ± 0.2	8.5 ± 1.0	<.001	4.2 ± 1.1	NS	<.01
CD4⁺CD25^high/CD8⁺	6.4 ± 0.7	16.6 ± 5.4	NS	3.9 ± 1.2	NS	<.01

		No GvHD			Acute GvHD
Cell type	Healthy ctrls, % of total lymphocytes	% of total lymphocytes	P vs healthy ctrls	% of total lymphocytes	P vs healthy ctrls	P vs no GvHD
CD4⁺/CD3⁺	57.4 ± 4.6	49.3 ± 6.8	NS	42.9 ± 5.5	NS	NS
CD8⁺/CD3⁺	37.2 ± 2.7	38.9 ± 5.3	NS	55.4 ± 4.2	<.01	<.05
CD4⁺CD25^high/CD3⁺	1.0 ± 0.1	2.8 ± 0.6	<.01	0.8 ± 0.2	NS	<.001
CD4⁺CD25^high/CD4⁺	2.3 ± 0.2	8.5 ± 1.0	<.001	4.2 ± 1.1	NS	<.01
CD4⁺CD25^high/CD8⁺	6.4 ± 0.7	16.6 ± 5.4	NS	3.9 ± 1.2	NS	<.01

Analyses were performed by flow cytometry of whole blood samples from healthy controls (n = 5), as well as allografted symptomatic patients without GvHD (n = 10) and with acute GvHD (n = 16). Results are expressed as mean ± SEM.

NS indicates not significant.

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