Table 3.

Multivariate analysis of grades II to IV acute GVHD




Relative risk of grades II to IV acute GVHD (95% CI)

P
HLA-identical sibling BM   
   G-CSF+ within 7 days after transplantation vs no G-CSF*  1.11 (0.86-1.42)   .42  
   Age   1.02 (1.01-1.03)   .001  
   KPS more than 80* vs less than 80%   1.62 (1.28-2.03)   .001  
   TBI vs no TBI*  1.40 (1.12-1.74)   .003  
   CML vs AML*  1.29 (1.04-2.58)   .002  
HLA-identical sibling PBSCs   
   G-CSF+ within 7 days after transplantation vs no G-CSF*  1.21 (0.95-1.62)   .11  
Matched unrelated donor BM   
   G-CSF+ within 7 days after transplantation vs no G-CSF*  0.83 (1.07-1.72)   .10  
   CML vs AML*
 
1.35 (1.07-1.72)
 
.01
 



Relative risk of grades II to IV acute GVHD (95% CI)

P
HLA-identical sibling BM   
   G-CSF+ within 7 days after transplantation vs no G-CSF*  1.11 (0.86-1.42)   .42  
   Age   1.02 (1.01-1.03)   .001  
   KPS more than 80* vs less than 80%   1.62 (1.28-2.03)   .001  
   TBI vs no TBI*  1.40 (1.12-1.74)   .003  
   CML vs AML*  1.29 (1.04-2.58)   .002  
HLA-identical sibling PBSCs   
   G-CSF+ within 7 days after transplantation vs no G-CSF*  1.21 (0.95-1.62)   .11  
Matched unrelated donor BM   
   G-CSF+ within 7 days after transplantation vs no G-CSF*  0.83 (1.07-1.72)   .10  
   CML vs AML*
 
1.35 (1.07-1.72)
 
.01
 

BM indicates bone marrow; G-CSF, granulocyte colony-stimulating factor; KPS, Karnofsky performance status; CML, chronic myeloid leukemia; AML, acute myeloid leukemia; and PBSC, peripheral blood stem cell.

*

Reference group

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