Multivariate analysis of grades II to IV acute GVHD
. | Relative risk of grades II to IV acute GVHD (95% CI) . | P . |
---|---|---|
HLA-identical sibling BM | ||
G-CSF+ within 7 days after transplantation vs no G-CSF* | 1.11 (0.86-1.42) | .42 |
Age | 1.02 (1.01-1.03) | .001 |
KPS more than 80* vs less than 80% | 1.62 (1.28-2.03) | .001 |
TBI vs no TBI* | 1.40 (1.12-1.74) | .003 |
CML vs AML* | 1.29 (1.04-2.58) | .002 |
HLA-identical sibling PBSCs | ||
G-CSF+ within 7 days after transplantation vs no G-CSF* | 1.21 (0.95-1.62) | .11 |
Matched unrelated donor BM | ||
G-CSF+ within 7 days after transplantation vs no G-CSF* | 0.83 (1.07-1.72) | .10 |
CML vs AML* | 1.35 (1.07-1.72) | .01 |
. | Relative risk of grades II to IV acute GVHD (95% CI) . | P . |
---|---|---|
HLA-identical sibling BM | ||
G-CSF+ within 7 days after transplantation vs no G-CSF* | 1.11 (0.86-1.42) | .42 |
Age | 1.02 (1.01-1.03) | .001 |
KPS more than 80* vs less than 80% | 1.62 (1.28-2.03) | .001 |
TBI vs no TBI* | 1.40 (1.12-1.74) | .003 |
CML vs AML* | 1.29 (1.04-2.58) | .002 |
HLA-identical sibling PBSCs | ||
G-CSF+ within 7 days after transplantation vs no G-CSF* | 1.21 (0.95-1.62) | .11 |
Matched unrelated donor BM | ||
G-CSF+ within 7 days after transplantation vs no G-CSF* | 0.83 (1.07-1.72) | .10 |
CML vs AML* | 1.35 (1.07-1.72) | .01 |
BM indicates bone marrow; G-CSF, granulocyte colony-stimulating factor; KPS, Karnofsky performance status; CML, chronic myeloid leukemia; AML, acute myeloid leukemia; and PBSC, peripheral blood stem cell.
Reference group