Table 4.

Results of allogeneic stem cell transplantation with nonmyeloablative regimens for CLL


Study

No. patients

NRM, % (follow-up time, y)

Conditioning regimen

Patients with related donor, %

PFS, % (year of projection)

OS, % (year of projection)
Dreger et al (EBMT, 2003)90   77   18 (1)   Several   82   56 (2)   72 (2)  
Schetelig et al (2003)91   30   15 (2)   Fluda + Bu + ATG   50   67 (2)   72 (2)  
Khouri et al (2004)92   17   22 (2)   Fluda + Cy ± Rituximab   100   60 (2)   80 (2)  
Sorror et al (2005)93 
 
64
 
22 (2)
 
Fluda ± TBI (2 Gy)
 
69
 
52 (2)
 
60 (2)
 

Study

No. patients

NRM, % (follow-up time, y)

Conditioning regimen

Patients with related donor, %

PFS, % (year of projection)

OS, % (year of projection)
Dreger et al (EBMT, 2003)90   77   18 (1)   Several   82   56 (2)   72 (2)  
Schetelig et al (2003)91   30   15 (2)   Fluda + Bu + ATG   50   67 (2)   72 (2)  
Khouri et al (2004)92   17   22 (2)   Fluda + Cy ± Rituximab   100   60 (2)   80 (2)  
Sorror et al (2005)93 
 
64
 
22 (2)
 
Fluda ± TBI (2 Gy)
 
69
 
52 (2)
 
60 (2)
 

NRM indicates nonrelapse mortality; PFS, progression-free survival; OS, overall survival; Fluda, fludarabine; Bu, busulfan; ATG, antithymocyte globulin; and Cy, cyclophosphamide.

Close Modal

or Create an Account

Close Modal
Close Modal