Clinical characteristics of PNH+ and PNH- patients
. | PNH+ . | PNH- . | P . |
|---|---|---|---|
| No. of patients | 83 | 39 | NA |
| Median age, y (range) | 57 (13-83) | 54 (12-83) | .16 |
| Sex, M/F | 36/47 | 19/20 | .58 |
| Severity, severe/moderate | 53/30 | 22/17 | .43 |
| Chromosome abnormality, no. of patients | 7 | 3 | .88 |
| –7 | 0 | 1 | |
| +8 | 2 | 1 | |
| –Y | 3 | 0 | |
| Others | 2 | 1 | |
| Median WBC count, × 109 (range) | 2.1 (0.5-4.3) | 1.9 (0.7-3.2) | .15 |
| Median neutrophil count, × 109/L (range) | 0.53 (0.02-2.2) | 0.49 (0.01-2.7) | .65 |
| Median hemoglobin level, g/L (range) | 67 (32-140) | 67 (40-108) | .92 |
| Mean corpuscular volume, fL (range) | 101.5 (84.2-123.5) | 98.5 (77.2-118.0) | .13 |
| Median platelet count, × 109/L (range) | 14.0 (2.0-60.0) | 16.0 (1.0-87.0) | .65 |
| Median reticulocyte count, × 109/L (range) | 19.0 (3.0-90.0) | 24.0 (2.0-106.0) | .50 |
| Median time from diagnosis to IST, d (range) | 30 (1-334) | 33 (2-268) | .46 |
| No. of patients who received G-CSF during IST | 25 | 12 | .94 |
. | PNH+ . | PNH- . | P . |
|---|---|---|---|
| No. of patients | 83 | 39 | NA |
| Median age, y (range) | 57 (13-83) | 54 (12-83) | .16 |
| Sex, M/F | 36/47 | 19/20 | .58 |
| Severity, severe/moderate | 53/30 | 22/17 | .43 |
| Chromosome abnormality, no. of patients | 7 | 3 | .88 |
| –7 | 0 | 1 | |
| +8 | 2 | 1 | |
| –Y | 3 | 0 | |
| Others | 2 | 1 | |
| Median WBC count, × 109 (range) | 2.1 (0.5-4.3) | 1.9 (0.7-3.2) | .15 |
| Median neutrophil count, × 109/L (range) | 0.53 (0.02-2.2) | 0.49 (0.01-2.7) | .65 |
| Median hemoglobin level, g/L (range) | 67 (32-140) | 67 (40-108) | .92 |
| Mean corpuscular volume, fL (range) | 101.5 (84.2-123.5) | 98.5 (77.2-118.0) | .13 |
| Median platelet count, × 109/L (range) | 14.0 (2.0-60.0) | 16.0 (1.0-87.0) | .65 |
| Median reticulocyte count, × 109/L (range) | 19.0 (3.0-90.0) | 24.0 (2.0-106.0) | .50 |
| Median time from diagnosis to IST, d (range) | 30 (1-334) | 33 (2-268) | .46 |
| No. of patients who received G-CSF during IST | 25 | 12 | .94 |
NA indicates not applicable.