Table 4.

Summary of median transcript levels in DS and non-DS megakaryoblast samples


Gene

DS AMkL

Non-DS AMkL

Fold difference by real-time PCR

P

Fold difference by microarray
BST2  0.220   1.600   7.3   .004   8.5  
KRT18  1.430   26.020   18.2   .020   5.7  
DUSP6  0.600   3.150   5.3   .003   7.9  
BCL2  0.163   1.067   6.5   .070   5.1  
CD36  1.473   0.476   3.1   .012   4.6  
RHAG  0.185   0.114   1.6   .384   8.6  
MDR1
 
0.881
 
0.430
 
2.0
 
.195
 
4.5
 

Gene

DS AMkL

Non-DS AMkL

Fold difference by real-time PCR

P

Fold difference by microarray
BST2  0.220   1.600   7.3   .004   8.5  
KRT18  1.430   26.020   18.2   .020   5.7  
DUSP6  0.600   3.150   5.3   .003   7.9  
BCL2  0.163   1.067   6.5   .070   5.1  
CD36  1.473   0.476   3.1   .012   4.6  
RHAG  0.185   0.114   1.6   .384   8.6  
MDR1
 
0.881
 
0.430
 
2.0
 
.195
 
4.5
 

Data are shown for median transcript levels determined by real-time RT-PCR assays, as described in “Materials and methods.” Statistical differences between the groups for the real-time RT-PCR results were determined by the nonparametric Mann-Whitney 2-sample test.

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