Table 4.

Causes of death in the first 3 months during the IFM 95-01 trial analyzed by treatment allocation*


Causes of death

Total no. patients

MP

M-DEX

DEX

DEX-IFN
Myeloma progression   13   1   0   3   9  
Died unexpectedly at home; cause not known   3   0   0   3   0  
Pyogenic infection when tumor load not immediately life threatening   12   3   1   5   3  
Cardiac   2   1   1   0   0  
Neurologic   1   0   1   0   0  
Perforated diverticulum   1   0   0   0   1  
Hemorrhage   1   0   0   1   0  
Amyloidosis   1   1   0   0   0  
MDS/secondary leukemia   0   0   0   0   0  
Other cancer   0   0   0   0   0  
Other causes
 
4
 
0
 
0
 
0
 
1
 

Causes of death

Total no. patients

MP

M-DEX

DEX

DEX-IFN
Myeloma progression   13   1   0   3   9  
Died unexpectedly at home; cause not known   3   0   0   3   0  
Pyogenic infection when tumor load not immediately life threatening   12   3   1   5   3  
Cardiac   2   1   1   0   0  
Neurologic   1   0   1   0   0  
Perforated diverticulum   1   0   0   0   1  
Hemorrhage   1   0   0   1   0  
Amyloidosis   1   1   0   0   0  
MDS/secondary leukemia   0   0   0   0   0  
Other cancer   0   0   0   0   0  
Other causes
 
4
 
0
 
0
 
0
 
1
 

The data were collected for 488 patients; for MP, n = 122; for M-DEX, n = 118; for DEX, n = 127; for DEX-IFN, n = 121.

*

Deaths in the first month were as follows: MP, 1 patient; M-DEX, 1 patient; DEX, 5 patients; DEX-IFN, 6 patients

Suicide

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