Table 2.

Incidence and severity of acute and chronic graft-versus-host disease in the 137 patients who did not satisfy criteria for molecular relapse


Severity of GvHD

Persistently negative

Fluctuating positive

Persistently positive
No. patients   36   51   27  
aGvHD, no. (%)    
    Grades 0-1   15 (42)   30 (59)   19 (70)  
    Grades 2-4   21 (58)   21 (41)   8 (30)  
cGvHD, no. (%)    
    Nil   9 (25)   22 (44)   8 (30)  
    Limited or extensive
 
27 (75)
 
28 (56)
 
19 (70)
 

Severity of GvHD

Persistently negative

Fluctuating positive

Persistently positive
No. patients   36   51   27  
aGvHD, no. (%)    
    Grades 0-1   15 (42)   30 (59)   19 (70)  
    Grades 2-4   21 (58)   21 (41)   8 (30)  
cGvHD, no. (%)    
    Nil   9 (25)   22 (44)   8 (30)  
    Limited or extensive
 
27 (75)
 
28 (56)
 
19 (70)
 

The relationship between severity of aGvHD and the pattern of molecular positivity is significant (P = .039, chi-square trend test), but there is no significant relationship between severity of cGvHD and pattern of molecular disease (P = .71). Numbers in parentheses are percentages.

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