Table 5.

CR, OS, and EFS in 1560 patients for whom clinical data are available



Total no. patients

No. patients

CR

Median OS

Median EFS

NRASmut
NRASWT
NRASmut, %
NRASWT, %
P
NRASmut, d
NRASWT, d
P
NRASmut, d
NRASWT, d
P
All patients   1560   160   1400   60.6   55.7   .340   1490   604   .096   424   335   .146  
Normal karyotype   733   59   674   65.9   64.2   .620   1012   737   .934   368   352   .947  
All intermediate karyotypes   299   27   272   62.7   60.9   .748   310   436   .672   187   303   .138  
inv(16)   113   41   72   66.7   71.8   .429   NR   NR   .456   918   769   .956  
inv(3)   20   4   16   NA   NA   NA   100   752   .320   100   296   .835  
t(8;21)
 
116
 
13
 
103
 
80
 
62.8
 
.250
 
NR
 
882
 
.453
 
NR
 
648
 
.175
 


Total no. patients

No. patients

CR

Median OS

Median EFS

NRASmut
NRASWT
NRASmut, %
NRASWT, %
P
NRASmut, d
NRASWT, d
P
NRASmut, d
NRASWT, d
P
All patients   1560   160   1400   60.6   55.7   .340   1490   604   .096   424   335   .146  
Normal karyotype   733   59   674   65.9   64.2   .620   1012   737   .934   368   352   .947  
All intermediate karyotypes   299   27   272   62.7   60.9   .748   310   436   .672   187   303   .138  
inv(16)   113   41   72   66.7   71.8   .429   NR   NR   .456   918   769   .956  
inv(3)   20   4   16   NA   NA   NA   100   752   .320   100   296   .835  
t(8;21)
 
116
 
13
 
103
 
80
 
62.8
 
.250
 
NR
 
882
 
.453
 
NR
 
648
 
.175
 

NR indicates not reached; NA, not available.

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