CR, OS, and EFS in 1560 patients for whom clinical data are available
. | Total no. patients . | No. patients . | . | CR . | . | . | Median OS . | . | . | Median EFS . | . | . | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
. | . | NRASmut . | NRASWT . | NRASmut, % . | NRASWT, % . | P . | NRASmut, d . | NRASWT, d . | P . | NRASmut, d . | NRASWT, d . | P . | |||||||
All patients | 1560 | 160 | 1400 | 60.6 | 55.7 | .340 | 1490 | 604 | .096 | 424 | 335 | .146 | |||||||
Normal karyotype | 733 | 59 | 674 | 65.9 | 64.2 | .620 | 1012 | 737 | .934 | 368 | 352 | .947 | |||||||
All intermediate karyotypes | 299 | 27 | 272 | 62.7 | 60.9 | .748 | 310 | 436 | .672 | 187 | 303 | .138 | |||||||
inv(16) | 113 | 41 | 72 | 66.7 | 71.8 | .429 | NR | NR | .456 | 918 | 769 | .956 | |||||||
inv(3) | 20 | 4 | 16 | NA | NA | NA | 100 | 752 | .320 | 100 | 296 | .835 | |||||||
t(8;21) | 116 | 13 | 103 | 80 | 62.8 | .250 | NR | 882 | .453 | NR | 648 | .175 |
. | Total no. patients . | No. patients . | . | CR . | . | . | Median OS . | . | . | Median EFS . | . | . | |||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
. | . | NRASmut . | NRASWT . | NRASmut, % . | NRASWT, % . | P . | NRASmut, d . | NRASWT, d . | P . | NRASmut, d . | NRASWT, d . | P . | |||||||
All patients | 1560 | 160 | 1400 | 60.6 | 55.7 | .340 | 1490 | 604 | .096 | 424 | 335 | .146 | |||||||
Normal karyotype | 733 | 59 | 674 | 65.9 | 64.2 | .620 | 1012 | 737 | .934 | 368 | 352 | .947 | |||||||
All intermediate karyotypes | 299 | 27 | 272 | 62.7 | 60.9 | .748 | 310 | 436 | .672 | 187 | 303 | .138 | |||||||
inv(16) | 113 | 41 | 72 | 66.7 | 71.8 | .429 | NR | NR | .456 | 918 | 769 | .956 | |||||||
inv(3) | 20 | 4 | 16 | NA | NA | NA | 100 | 752 | .320 | 100 | 296 | .835 | |||||||
t(8;21) | 116 | 13 | 103 | 80 | 62.8 | .250 | NR | 882 | .453 | NR | 648 | .175 |
NR indicates not reached; NA, not available.