Distribution of mutations in codons 12, 13, and 61 in all patients with NRAS mutations and in patients with inv(16)/t(16;16) and inv(3)/t(3;3)
Codon . | All NRAS mutations, no. (%) . | NRASmut inv(16)/t(16;16), no. (%) . | NRASmut inv(3)/t(3;3), no. (%) . |
|---|---|---|---|
| 12 | 112 (43.6) | 14 (28.0) | 4 (36.4) |
| 13 | 54 (21.0) | 10 (20.0) | 1 (9.1) |
| 61 | 64 (24.9) | 21 (42.0) | 6 (54.5) |
| Not sequenced | 27 (10.5) | 5 (10.0) | 0 (0.0) |
| Total | 257 (100.0) | 50 (100.0) | 11 (100.0) |
Codon . | All NRAS mutations, no. (%) . | NRASmut inv(16)/t(16;16), no. (%) . | NRASmut inv(3)/t(3;3), no. (%) . |
|---|---|---|---|
| 12 | 112 (43.6) | 14 (28.0) | 4 (36.4) |
| 13 | 54 (21.0) | 10 (20.0) | 1 (9.1) |
| 61 | 64 (24.9) | 21 (42.0) | 6 (54.5) |
| Not sequenced | 27 (10.5) | 5 (10.0) | 0 (0.0) |
| Total | 257 (100.0) | 50 (100.0) | 11 (100.0) |
Frequency of involvement of codon 61 in comparison with involvement of codons 12 and 13, P < .001.