Table 2.

Primary and secondary outcomes by anemia status and CKD category



No anemia

Anemia
Outcome
No.
Age-*and sex-adjusted rate per 100 person-years (95% CI)
No.
Age-*and sex-adjusted rate per 100 person-years (95% CI)
Hazard ratios(95% CI)
GFR, 60 mL/min per 1.73 m2      
    All-cause mortality   999   2.39 (2.24-2.54)   122   11.92 (9.95-14.28)   4.29 (3.55-5.12)  
    All-cause hospitalization   4770   15.24 (14.81-15.67)   220   38.80 (33.98-44.36)   2.16 (1.88-2.48)  
    CVD-specific hospitalization   1318   4.18 (3.96-4.41)   83   13.44 (10.82-16.69)   2.49 (1.99-3.12)  
GFR, 30 to 59 mL/min per 1.73 m2      
    All-cause mortality   565   4.00 (3.65-4.38)   114   11.95 (9.90-14.42)   2.80 (2.28-3.43)  
    All-cause hospitalization   1747   20.05 (19.10-21.06)   202   42.46 (36.94-48.80)   1.87 (1.61-2.12)  
    CVD-specific hospitalization   717   7.38 (6.82-7.99)   102   18.38 (15.08-22.39)   2.15 (1.74-2.65)  
GFR, less than 30 mL/min per 1.73 m2      
    All-cause mortality   117   9.20 (7.64-11.07)   66   14.61 (11.43-18.67)   1.53 (1.12-2.07)  
    All-cause hospitalization   230   34.72 (30.48-39.55)   109   46.33 (38.36-55.97)   1.23 (0.97-1.56)  
    CVD-specific hospitalization
 
127
 
17.24 (14.44-20.59)
 
60
 
21.40 (16.56-27.65)
 
1.15 (0.84-1.59)
 


No anemia

Anemia
Outcome
No.
Age-*and sex-adjusted rate per 100 person-years (95% CI)
No.
Age-*and sex-adjusted rate per 100 person-years (95% CI)
Hazard ratios(95% CI)
GFR, 60 mL/min per 1.73 m2      
    All-cause mortality   999   2.39 (2.24-2.54)   122   11.92 (9.95-14.28)   4.29 (3.55-5.12)  
    All-cause hospitalization   4770   15.24 (14.81-15.67)   220   38.80 (33.98-44.36)   2.16 (1.88-2.48)  
    CVD-specific hospitalization   1318   4.18 (3.96-4.41)   83   13.44 (10.82-16.69)   2.49 (1.99-3.12)  
GFR, 30 to 59 mL/min per 1.73 m2      
    All-cause mortality   565   4.00 (3.65-4.38)   114   11.95 (9.90-14.42)   2.80 (2.28-3.43)  
    All-cause hospitalization   1747   20.05 (19.10-21.06)   202   42.46 (36.94-48.80)   1.87 (1.61-2.12)  
    CVD-specific hospitalization   717   7.38 (6.82-7.99)   102   18.38 (15.08-22.39)   2.15 (1.74-2.65)  
GFR, less than 30 mL/min per 1.73 m2      
    All-cause mortality   117   9.20 (7.64-11.07)   66   14.61 (11.43-18.67)   1.53 (1.12-2.07)  
    All-cause hospitalization   230   34.72 (30.48-39.55)   109   46.33 (38.36-55.97)   1.23 (0.97-1.56)  
    CVD-specific hospitalization
 
127
 
17.24 (14.44-20.59)
 
60
 
21.40 (16.56-27.65)
 
1.15 (0.84-1.59)
 

Absence of anemia is defined as Hb at or above 110 g/L; anemia was defined as Hb below 110 g/L.

*

Age adjusted to the sample mean using Poisson regression.

Adjusted for age, sex, diabetes mellitus, and comorbidity.

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