Predictive value of presence of APLA subtypes, IgG or IgM combined, for the risk of thrombotic events; persistent versus persistent or transient antibodies
APLA subtype . | Sensitivity, % . | Specificity, % . | NPV, % . | PPV, % . |
|---|---|---|---|---|
| Lupus anticoagulant | ||||
| Persistent | 100 | 84 | 100 | 47 |
| Persistent or transient | 100 | 73 | 100 | 33 |
| ACLA: IgG or IgM | ||||
| Persistent | 71 | 86 | 96 | 42 |
| Persistent or transient | 71 | 53 | 93 | 17 |
| Anti-β2-GPI: IgG or IgM | ||||
| Persistent | 86 | 79 | 97 | 40 |
| Persistent or transient | 86 | 67 | 97 | 30 |
| Anti-PT: IgG or IgM | ||||
| Persistent | 57 | 78 | 92 | 29 |
| Persistent or transient | 71 | 51 | 92 | 19 |
APLA subtype . | Sensitivity, % . | Specificity, % . | NPV, % . | PPV, % . |
|---|---|---|---|---|
| Lupus anticoagulant | ||||
| Persistent | 100 | 84 | 100 | 47 |
| Persistent or transient | 100 | 73 | 100 | 33 |
| ACLA: IgG or IgM | ||||
| Persistent | 71 | 86 | 96 | 42 |
| Persistent or transient | 71 | 53 | 93 | 17 |
| Anti-β2-GPI: IgG or IgM | ||||
| Persistent | 86 | 79 | 97 | 40 |
| Persistent or transient | 86 | 67 | 97 | 30 |
| Anti-PT: IgG or IgM | ||||
| Persistent | 57 | 78 | 92 | 29 |
| Persistent or transient | 71 | 51 | 92 | 19 |
NPV indicates negative predictive value; PPV, positive predictive value.