Table 2.

Evaluating dispersion of LANA1 due to scFv expression in BC-1 cells


scFv

Total no. of cells counted

Mean no. of LANA1

P: scFv vs untransfected

P: scFv vs 4BL
BM9   10   9.5   < .001   < .001  
BM10   13   18.54   < .001   < .001  
4BL/control   3   41.67   .49   NA  
Untransfected
 
7
 
38.44
 
NA
 
NA
 

scFv

Total no. of cells counted

Mean no. of LANA1

P: scFv vs untransfected

P: scFv vs 4BL
BM9   10   9.5   < .001   < .001  
BM10   13   18.54   < .001   < .001  
4BL/control   3   41.67   .49   NA  
Untransfected
 
7
 
38.44
 
NA
 
NA
 

LANA1 spots were counted and the Student t test effectuated to statistically compare between scFvs and controls. Student t tests P values for average differences, assuming equal variances and unpaired; 2-tailed for among controls or among treatment comparisons and 1-tailed for treatment versus controls.

NA indicates not applicable.