Permeation and mechanical properties of α251 and control recombinant fibrin formed with and without factor XIIIa
. | Q/t, mL/h . | Ks, cm2 109 . | G′, dyne/cm2 . | G″, dyne/cm2 . | G″/G′ . |
|---|---|---|---|---|---|
| Control | ND | ND | 164 ± 48 | 10.7 ± 1.2 | 0.067 ± 0.01 |
| α251 | ND | ND | 66 ± 24* | 6.1 ± 1.6* | 0.094 ± 0.01* |
| Control + XIIIa | 4.3 ± 2.2 | 7.9 ± 3.3 | 369 ± 63 | 14.1 ± 2.4 | 0.037 ± 0.01 |
| α251 + XIIIa | 1.9 ± 0.9† | 4.3 ± 2.2† | 106 ± 43† | 7.2 ± 3.9† | 0.063 ± 0.011† |
. | Q/t, mL/h . | Ks, cm2 109 . | G′, dyne/cm2 . | G″, dyne/cm2 . | G″/G′ . |
|---|---|---|---|---|---|
| Control | ND | ND | 164 ± 48 | 10.7 ± 1.2 | 0.067 ± 0.01 |
| α251 | ND | ND | 66 ± 24* | 6.1 ± 1.6* | 0.094 ± 0.01* |
| Control + XIIIa | 4.3 ± 2.2 | 7.9 ± 3.3 | 369 ± 63 | 14.1 ± 2.4 | 0.037 ± 0.01 |
| α251 + XIIIa | 1.9 ± 0.9† | 4.3 ± 2.2† | 106 ± 43† | 7.2 ± 3.9† | 0.063 ± 0.011† |
For each polymerization condition, 2 separate experiments were performed in triplicate. Data are expressed as mean ± SEM.
ND indicates not determined; Q/t, mL/h indicates flow rate.
Indicates significant differences (P < .05) between control and α251 recombinant fibrin that are not cross-linked.
Indicates significant differences (P < .05) between control and α251 recombinant fibrin that are cross-linked.