Summary of patients with TDT and transfusion characteristics
| Patients with TDT | |
| Patients, N | 36 |
| Age, y | 48.75 (44.91-52.59) |
| Sex, male/female | 13/23 |
| Body mass index | 23.35 (22.51-24.18) |
| Smoking, n | 10 |
| ABO | 14A, 6B, 16O |
| Rhesus, +/− | 33/3 |
| β++/β++ or β++/β+ (mild deficiency), n | 10 |
| β+/β+ or β0/β++ (moderate deficiency), n | 18 |
| β0/β+ or β0/β0 (severe deficiency), n | 7∗ |
| Extramedullary hematopoiesis, yes/no | 11/25 |
| Splenectomy, yes/no | 22/14 |
| Cholecystectomy, yes/no | 17/19 |
| Hypogonadism, yes/no | 17/19 |
| Hypothyroidism, yes/no | 14/22 |
| Osteopenia, yes/no | 12/24 |
| Osteoporosis, yes/no | 17/19 |
| Pulmonary hypertension, yes/no | 7/29 |
| Atrial fibrillation, yes/no | 8/28 |
| Ferriprox, n | 11 |
| Exjade, n | 10 |
| Desferal, n | 3 |
| Ferriprox and Desferal, n | 9 |
| Ferriprox and Exjade, n | 2 |
| No chelation, n | 1 |
| Age of first transfusion, y | 16.06 (8.45-23.66) |
| Duration of transfusion therapy, y | 32.67 (26.42-38.91) |
| Interval since previous transfusion, d | 18.42 (16.03-20.80) |
| Average transfusion interval, d | 16.75 (15.63-17.87) |
| Units per transfusion, n | 1 unit, 13; 2 units, 23 |
| Donors and RBC units | |
| Donors/units, N | 58 |
| Age, y | 43.26 (40.80-45.72) |
| Sex, male/female | 45/13 |
| First-time donors, n | 10 |
| Storage age, d | 9.39 (7.42-11.36) |
| Total volume transfused,† mL | 537.5 (480.4-594.6) |
| RBC unit Hb, g | 92.73 (83.33-102.1) |
| Patients with TDT | |
| Patients, N | 36 |
| Age, y | 48.75 (44.91-52.59) |
| Sex, male/female | 13/23 |
| Body mass index | 23.35 (22.51-24.18) |
| Smoking, n | 10 |
| ABO | 14A, 6B, 16O |
| Rhesus, +/− | 33/3 |
| β++/β++ or β++/β+ (mild deficiency), n | 10 |
| β+/β+ or β0/β++ (moderate deficiency), n | 18 |
| β0/β+ or β0/β0 (severe deficiency), n | 7∗ |
| Extramedullary hematopoiesis, yes/no | 11/25 |
| Splenectomy, yes/no | 22/14 |
| Cholecystectomy, yes/no | 17/19 |
| Hypogonadism, yes/no | 17/19 |
| Hypothyroidism, yes/no | 14/22 |
| Osteopenia, yes/no | 12/24 |
| Osteoporosis, yes/no | 17/19 |
| Pulmonary hypertension, yes/no | 7/29 |
| Atrial fibrillation, yes/no | 8/28 |
| Ferriprox, n | 11 |
| Exjade, n | 10 |
| Desferal, n | 3 |
| Ferriprox and Desferal, n | 9 |
| Ferriprox and Exjade, n | 2 |
| No chelation, n | 1 |
| Age of first transfusion, y | 16.06 (8.45-23.66) |
| Duration of transfusion therapy, y | 32.67 (26.42-38.91) |
| Interval since previous transfusion, d | 18.42 (16.03-20.80) |
| Average transfusion interval, d | 16.75 (15.63-17.87) |
| Units per transfusion, n | 1 unit, 13; 2 units, 23 |
| Donors and RBC units | |
| Donors/units, N | 58 |
| Age, y | 43.26 (40.80-45.72) |
| Sex, male/female | 45/13 |
| First-time donors, n | 10 |
| Storage age, d | 9.39 (7.42-11.36) |
| Total volume transfused,† mL | 537.5 (480.4-594.6) |
| RBC unit Hb, g | 92.73 (83.33-102.1) |