Table 3. The results of the infection... | American Society of Hematology

Table 3.

The results of the infection per patient analysis and the infection rate per patient-month analysis

Infection type	Product	Pooled infection rate per patient	P value	Pooled infection rate per patient-month	P value
All-grade infections	CAR T	0.44	.18	0.0167	.0012∗
	CD28 CAR T	0.52	.77	0.0182	.006∗
	4-1BB CAR T	0.34	.02∗	0.0144	.02∗
	BsAbs	0.54	—	0.0397	—
Grade 3+ infections	CAR T	0.16	.08	0.0069	.0003∗
	CD28 CAR T	0.22	.98	0.0076	.01∗
	4-1BB CAR T	0.13	.003∗	0.0064	.0002∗
	BsAbs	0.22	—	0.0165	—
Infection-related mortality	CAR T	0.04	.26	0.0023	.89
	CD28 CAR T	0.07	.01∗	0.0024	.89
	4-1BB CAR T	0.03	.76	0.0023	.96
	BsAbs	0.03	—	0.0022	—

Infection type	Product	Pooled infection rate per patient	P value	Pooled infection rate per patient-month	P value
All-grade infections	CAR T	0.44	.18	0.0167	.0012∗
	CD28 CAR T	0.52	.77	0.0182	.006∗
	4-1BB CAR T	0.34	.02∗	0.0144	.02∗
	BsAbs	0.54	—	0.0397	—
Grade 3+ infections	CAR T	0.16	.08	0.0069	.0003∗
	CD28 CAR T	0.22	.98	0.0076	.01∗
	4-1BB CAR T	0.13	.003∗	0.0064	.0002∗
	BsAbs	0.22	—	0.0165	—
Infection-related mortality	CAR T	0.04	.26	0.0023	.89
	CD28 CAR T	0.07	.01∗	0.0024	.89
	4-1BB CAR T	0.03	.76	0.0023	.96
	BsAbs	0.03	—	0.0022	—

The P values are taken from the subgroup analyses described in the text comparing all CAR T, CD28-based CAR T, and 4-1BB–based CAR T with BsAbs.

Boldface values are statistically significant.