Transplantation outcome of the 83 patients with DDX41mut patients
| Outcomes . | All patients (N = 83) . | AML (n = 64) . | MDS (n = 19) . |
|---|---|---|---|
| Estimation (95% CI) . | Estimation (95% CI) . | Estimation (95% CI) . | |
| Median FU, y | 4.7 (3.4-5.9) | 4.8 (3.4-6.5) | 3.9 (1.9-5.9) |
| OS (2 years) | 73.9 (62.8-82.1) | 72.7 (59.7-82.1) | 78 (51.5-91.1) |
| LFS (2 years) | 68.9 (57.5-77.8) | 71.2 (58.3-80.8) | 61.3 (35.5-79.3) |
| RI (2 years) | 10.2 (4.7-18.1) | 6.5 (2.1-14.7) | 22.3 (6.6-43.7) |
| NRM (2 years) | 21 (12.8-30.5) | 22.2 (12.8-33.2) | 16.4 (3.8-36.9) |
| aGVHD-II/IV (100 days) | 28 (18.8-38.1) | 25.4 (15.4-36.7) | 36.8 (15.9-58.1) |
| aGVHD-III/IV (100 days) | 14.6 (8-23.2) | 12.7 (5.9-22.2) | 21.1 (6.3-41.6) |
| cGVHD (2 years) | 39.2 (28.2-50.1) | 37.9 (25.6-50) | 43.7 (18.7-66.5) |
| cGVHD Ext (2 years) | 9.6 (4.2-17.7) | 6.9 (2.2-15.4) | 18.8 (4.3-41.3) |
| Outcomes . | All patients (N = 83) . | AML (n = 64) . | MDS (n = 19) . |
|---|---|---|---|
| Estimation (95% CI) . | Estimation (95% CI) . | Estimation (95% CI) . | |
| Median FU, y | 4.7 (3.4-5.9) | 4.8 (3.4-6.5) | 3.9 (1.9-5.9) |
| OS (2 years) | 73.9 (62.8-82.1) | 72.7 (59.7-82.1) | 78 (51.5-91.1) |
| LFS (2 years) | 68.9 (57.5-77.8) | 71.2 (58.3-80.8) | 61.3 (35.5-79.3) |
| RI (2 years) | 10.2 (4.7-18.1) | 6.5 (2.1-14.7) | 22.3 (6.6-43.7) |
| NRM (2 years) | 21 (12.8-30.5) | 22.2 (12.8-33.2) | 16.4 (3.8-36.9) |
| aGVHD-II/IV (100 days) | 28 (18.8-38.1) | 25.4 (15.4-36.7) | 36.8 (15.9-58.1) |
| aGVHD-III/IV (100 days) | 14.6 (8-23.2) | 12.7 (5.9-22.2) | 21.1 (6.3-41.6) |
| cGVHD (2 years) | 39.2 (28.2-50.1) | 37.9 (25.6-50) | 43.7 (18.7-66.5) |
| cGVHD Ext (2 years) | 9.6 (4.2-17.7) | 6.9 (2.2-15.4) | 18.8 (4.3-41.3) |
Ext, extensive; FU, follow-up; RI, relapse incidence.