Table 1.

Baseline demographics and laboratory studies, overall and by assigned treatment group

Total
N = 20
rVWF + TXA
n = 10
rVWF
n = 10
Age, y 29.0 (5.3) 29.1 (5.2) 28.8 (5.7) 
Race    
White 18 (90) 9 (90) 9 (90) 
Black 2 (10) 1 (10) 1 (10) 
Ethnicity    
Not Hispanic or Latino 20 (100) 10 (100) 10 (100) 
Height, cm 161.5 (8.3) 161.5 (10.6) 161.4 (5.5) 
Prepregnancy weight, kg 80.9 (23.7) 78.6 (29.0) 83.3 (18.1) 
Prepregnancy BMI, kg/m2 30.9 (8.4) 29.8 (9.8) 32.0 (7.0) 
Delivery weight, kg 94.4 (24.0) 93.5 (28.2) 95.3 (20.5) 
Delivery BMI, kg/m2 36.1 (8.1) 35.6 (9.3) 36.5 (7.3) 
Hemoglobin, g/dL  11.9 (0.9) 12.1 (0.9) 11.8 (1.0) 
Ferritin, ng/mL 15.8 (9.1) 18 (11.1) 13.5 (6.5) 
Low ferritin  20 (100) 10 (100) 10 (100) 
VWD type    
Type 1 20 (100) 10 (100) 10 (100) 
VWF:Ag, IU/mL  0.5 (0.3-1.9) 0.7 (0.3-1.9) 0.4 (0.3-0.7) 
VWF:RCo, IU/mL  0.3 (0.1-0.5) 0.4 (0.2-0.5) 0.3 (0.1-0.4) 
FVIII, IU/mL  0.7 (0.3-1.1) 0.6 (0.4-1.1) 0.6 (0.3-1.1) 
Total
N = 20
rVWF + TXA
n = 10
rVWF
n = 10
Age, y 29.0 (5.3) 29.1 (5.2) 28.8 (5.7) 
Race    
White 18 (90) 9 (90) 9 (90) 
Black 2 (10) 1 (10) 1 (10) 
Ethnicity    
Not Hispanic or Latino 20 (100) 10 (100) 10 (100) 
Height, cm 161.5 (8.3) 161.5 (10.6) 161.4 (5.5) 
Prepregnancy weight, kg 80.9 (23.7) 78.6 (29.0) 83.3 (18.1) 
Prepregnancy BMI, kg/m2 30.9 (8.4) 29.8 (9.8) 32.0 (7.0) 
Delivery weight, kg 94.4 (24.0) 93.5 (28.2) 95.3 (20.5) 
Delivery BMI, kg/m2 36.1 (8.1) 35.6 (9.3) 36.5 (7.3) 
Hemoglobin, g/dL  11.9 (0.9) 12.1 (0.9) 11.8 (1.0) 
Ferritin, ng/mL 15.8 (9.1) 18 (11.1) 13.5 (6.5) 
Low ferritin  20 (100) 10 (100) 10 (100) 
VWD type    
Type 1 20 (100) 10 (100) 10 (100) 
VWF:Ag, IU/mL  0.5 (0.3-1.9) 0.7 (0.3-1.9) 0.4 (0.3-0.7) 
VWF:RCo, IU/mL  0.3 (0.1-0.5) 0.4 (0.2-0.5) 0.3 (0.1-0.4) 
FVIII, IU/mL  0.7 (0.3-1.1) 0.6 (0.4-1.1) 0.6 (0.3-1.1) 

Data are mean ± standard deviation, (range), or n (%).

Hemoglobin at third-trimester screening visit.

Abnormally low ferritin is defined as <50 μg/L in the context of pregnancy.

VWF:RCo, VWF antigen, and FVIII clotting activity are historic (before pregnancy).

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