All grade 3 or higher AEs and serious AEs in arm C
| AE . | Arm C CPX-351 plus enasidenib (N = 7) . |
|---|---|
| Patients with any grade ≥3 AE by preferred term, n (%) | 7 (100) |
| Grade ≥3 hematologic AE, n (%) | |
| Febrile neutropenia | 7 (100) |
| Thrombocytopenia | 6 (86) |
| Neutropenia | 5 (71) |
| Anemia | 4 (57) |
| Leukopenia | 1 (14) |
| Grade ≥3 nonhematologic AE, n (%) | |
| Allergic transfusion reaction | 1 (14) |
| ALT increased | 1 (14) |
| Clostridium difficile infection | 1 (14) |
| Diarrhea | 1 (14) |
| Drug eruption | 1 (14) |
| Maculopapular rash | 1 (14) |
| Streptococcal bacteremia | 1 (14) |
| Patients with any serious AE by preferred term, n (%) | 3 (43) |
| Febrile neutropenia | 2 (29) |
| Pyrexia | 1 (14) |
| AE . | Arm C CPX-351 plus enasidenib (N = 7) . |
|---|---|
| Patients with any grade ≥3 AE by preferred term, n (%) | 7 (100) |
| Grade ≥3 hematologic AE, n (%) | |
| Febrile neutropenia | 7 (100) |
| Thrombocytopenia | 6 (86) |
| Neutropenia | 5 (71) |
| Anemia | 4 (57) |
| Leukopenia | 1 (14) |
| Grade ≥3 nonhematologic AE, n (%) | |
| Allergic transfusion reaction | 1 (14) |
| ALT increased | 1 (14) |
| Clostridium difficile infection | 1 (14) |
| Diarrhea | 1 (14) |
| Drug eruption | 1 (14) |
| Maculopapular rash | 1 (14) |
| Streptococcal bacteremia | 1 (14) |
| Patients with any serious AE by preferred term, n (%) | 3 (43) |
| Febrile neutropenia | 2 (29) |
| Pyrexia | 1 (14) |
All AEs were coded using Medical Dictionary for Regulatory Activities, version 21.1. Multiple entries for an individual patient under each preferred term were only counted once.
ALT, alanine aminotransferase.