The changes in evidence per recommendation and per outcome between the updated (2024) and original (2018) guideline
| Changes in evidence . | Number of recommendations (N = 16), n (%) . | Number of outcomes (N = 101), n (%) . |
|---|---|---|
| Noncomparative study to NRSI | 8 (50) | 32 (31.6) |
| No data to NRSI | 3 (18.8) | 4 (3.9) |
| Adult NRSI to pediatric NRSI | 2 (12.5) | 5 (4.9) |
| Noncomparative study to RCT | 1 (6.3) | 4 (3.9) |
| Changes in evidence . | Number of recommendations (N = 16), n (%) . | Number of outcomes (N = 101), n (%) . |
|---|---|---|
| Noncomparative study to NRSI | 8 (50) | 32 (31.6) |
| No data to NRSI | 3 (18.8) | 4 (3.9) |
| Adult NRSI to pediatric NRSI | 2 (12.5) | 5 (4.9) |
| Noncomparative study to RCT | 1 (6.3) | 4 (3.9) |
NRSI, nonrandomized studies of interventions; RCT, randomized controlled trials.