Table 3.

Demographics and clinical characteristics at baseline of patients with csEVH in the 301 study

VariableEculizumab (n = 30)Ravulizumab (n = 29)
Age at PNH diagnosis, n, mean ± SD (range), y 30
40.3 ± 17.0 (15-82) 
28
40.5 ± 16.6 (17-73) 
PNH clone size, mean ± SD (range)   
RBC type II 11.1 ± 13.7 (0.3-59.1) 11.1 ± 14.3 (0.3-50.2) 
RBC type III 22.7 ± 14.2 (2.4-63.3) 21.1 ± 15.1 (2.9-75.9) 
Total RBC 33.8 ± 22.3 (3.3-98.0) 32.3 ± 20.1 (9.2-78.0) 
Granulocytes 93.6 ± 5.3 (80.2-99.6) 92.2 ± 12.2 (43.9-99.9) 
Monocytes 94.7 ± 5.0 (83.3-99.9) 92.8 ± 14.0 (28.6-99.9) 
VariableEculizumab (n = 30)Ravulizumab (n = 29)
Age at PNH diagnosis, n, mean ± SD (range), y 30
40.3 ± 17.0 (15-82) 
28
40.5 ± 16.6 (17-73) 
PNH clone size, mean ± SD (range)   
RBC type II 11.1 ± 13.7 (0.3-59.1) 11.1 ± 14.3 (0.3-50.2) 
RBC type III 22.7 ± 14.2 (2.4-63.3) 21.1 ± 15.1 (2.9-75.9) 
Total RBC 33.8 ± 22.3 (3.3-98.0) 32.3 ± 20.1 (9.2-78.0) 
Granulocytes 93.6 ± 5.3 (80.2-99.6) 92.2 ± 12.2 (43.9-99.9) 
Monocytes 94.7 ± 5.0 (83.3-99.9) 92.8 ± 14.0 (28.6-99.9) 

SD, standard deviation.

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