Table 1.

Characteristics of the included donors

rs772557Donor typen (m:f)Median age, y (range)Median weight, kg (range)Median BMI (range)Donor relationshipDonor diagnosisMedian CD34+ level cells per μL (range)G-CSF+Plerixafor+Harvest day+No harvestMedian CD34+ yield (range)
RelatedUnrelatedMMOtherPrePostRatio
GG Allogeneic 7 (5:2) 28 (21-42) 80 (64-125) 24.4 (22.1-37.3) n/a n/a 2.3 (1.9-3.5) 21.8 (15.3-67.9) 8.4 (5.1-33.2) 8.4 (5.8-11) 
 Autologous 10 (6:4) 61 (41-71) 76 (60-106) 25.8 (22.6-32.7) n/a n/a 0.8 (0.3-2.2) 10.5 (1-45.7) 10 (0.1-36.6) 4.7 (3.3-11.6) 
AG Allogeneic 15 (12:3) 29 (19-55) 78 (62-105) 24.4 (20.2-30.1) 14 n/a n/a 1.9 (0.9-10.7) 38.9 (12-114.3) 16.9 (3-64) 7.3 (3.2-15.1) 
 Autologous 27 (20:7) 60 (38-69) 81 (58-104) 25.7 (19.8-36.7) n/a n/a 19 0.8 (0.2-6.7) 8.9 (0.6-26) 7.6 (0.1-26.6) 16 17 4.1 (2.4-8.9) 
AA Allogeneic 8 (6:2) 27 (20-38) 79 (58-116) 24.4 (18.8-32.5) n/a n/a 2.2 (0.5-5.1) 47.8 (12-76.9) 23 (6.9-75) 7.6 (3.3-15.9) 
 Autologous 19 (11:8) 61 (43-70) 70 (50-109) 24.8 (19.9-35-2) n/a n/a 16 1 (0.2-8.8) 5.5 (1.6-19.2) 4.9 (0.3-19.7) 15 15 3.6 (2-14) 
Total Allogeneic 31 (23:8) 29 (19-55) 78 (58-125) 24.4 (20.1-37.3) 27 n/a n/a 2.1 (0.5-10.7) 34.2 (12.1-114.3) 15.4 (3-75.1) 7.3 (3.2-15.9) 
 Autologous 56 (37:19) 60 (38-70) 77 (50-109) 24.8 (18.8-36.7) n/a n/a 43 13 0.8 (0.2-8.8) 8 (0.6-46.6) 7.4 (0.1-49.5) 39 41 3.9 (1.3-14) 
rs772557Donor typen (m:f)Median age, y (range)Median weight, kg (range)Median BMI (range)Donor relationshipDonor diagnosisMedian CD34+ level cells per μL (range)G-CSF+Plerixafor+Harvest day+No harvestMedian CD34+ yield (range)
RelatedUnrelatedMMOtherPrePostRatio
GG Allogeneic 7 (5:2) 28 (21-42) 80 (64-125) 24.4 (22.1-37.3) n/a n/a 2.3 (1.9-3.5) 21.8 (15.3-67.9) 8.4 (5.1-33.2) 8.4 (5.8-11) 
 Autologous 10 (6:4) 61 (41-71) 76 (60-106) 25.8 (22.6-32.7) n/a n/a 0.8 (0.3-2.2) 10.5 (1-45.7) 10 (0.1-36.6) 4.7 (3.3-11.6) 
AG Allogeneic 15 (12:3) 29 (19-55) 78 (62-105) 24.4 (20.2-30.1) 14 n/a n/a 1.9 (0.9-10.7) 38.9 (12-114.3) 16.9 (3-64) 7.3 (3.2-15.1) 
 Autologous 27 (20:7) 60 (38-69) 81 (58-104) 25.7 (19.8-36.7) n/a n/a 19 0.8 (0.2-6.7) 8.9 (0.6-26) 7.6 (0.1-26.6) 16 17 4.1 (2.4-8.9) 
AA Allogeneic 8 (6:2) 27 (20-38) 79 (58-116) 24.4 (18.8-32.5) n/a n/a 2.2 (0.5-5.1) 47.8 (12-76.9) 23 (6.9-75) 7.6 (3.3-15.9) 
 Autologous 19 (11:8) 61 (43-70) 70 (50-109) 24.8 (19.9-35-2) n/a n/a 16 1 (0.2-8.8) 5.5 (1.6-19.2) 4.9 (0.3-19.7) 15 15 3.6 (2-14) 
Total Allogeneic 31 (23:8) 29 (19-55) 78 (58-125) 24.4 (20.1-37.3) 27 n/a n/a 2.1 (0.5-10.7) 34.2 (12.1-114.3) 15.4 (3-75.1) 7.3 (3.2-15.9) 
 Autologous 56 (37:19) 60 (38-70) 77 (50-109) 24.8 (18.8-36.7) n/a n/a 43 13 0.8 (0.2-8.8) 8 (0.6-46.6) 7.4 (0.1-49.5) 39 41 3.9 (1.3-14) 

Other diagnoses include light-chain amyloidosis (n = 3), B-cell lymphoma (n = 6), T-cell lymphoma (n = 1), Waldenström disease (n = 1), isolated extramedullary plasmacytoma (n = 1), plasma cell leukemia (n = 1), Hodgkin lymphoma and MM (n = 1). G-CSF+ includes donors receiving additional G-CSF therapy to reach CD34+ yield. Plerixafor+ includes donors receiving additional plerixafor (CXCR4 inhibitor) to reach CD34+ yield. Harvest day+ refers to donors requiring an additional day of harvest (receiving additional G-CSF and/or plerixafor). No harvest refers to donors from whom no stem cells were collected. Pre refers to before mobilization therapy. Post refers to after mobilization therapy. Ratio represents mobilization efficiency.

BMI, body mass index; f, female; m, male; MM, multiple myeloma; n/a, not available.

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