AEs
| AE (N = 90) . | Any grade n (%) . | Grade ≥ 3 n (%) . | Grade 4 n (%) . |
|---|---|---|---|
| Diarrhea | 55 (61.1) | 2 (2.2) | 0 (0) |
| Rash (maculopapular) | 48 (53.3) | 10 (11.1) | 0 (0) |
| Fatigue | 47 (52.2) | 4 (4.4) | 0 (0) |
| Constipation | 44 (48.9) | 0 (0) | 0 (0) |
| Myalgia | 41 (45.6) | 0 (0) | 0 (0) |
| Cough | 30 (33.3) | 2 (2.2) | 0 (0) |
| Nausea | 27 (30) | 0 (0) | 0 (0) |
| Dyspnea | 23 (25.6) | 0 (0) | 0 (0) |
| Upper respiratory infection | 23 (25.6) | 1 (1) | 0 (0) |
| Fever | 21 (23.3) | 1 (1) | 0 (0) |
| Headache | 20 (22.2) | 1 (1) | 0 (0) |
| Neutropenia | 20 (22.2) | 7 (7.8) | 10 (11.1) |
| Allergic rhinitis | 16 (17.8) | 0 (0) | 0 (0) |
| Lower extremity edema | 14 (15.6) | 0 (0) | 0 (0) |
| Dizziness | 13 (14.4) | 0 (0) | 0 (0) |
| Pneumonia | 10 (11.1) | 6 (6.7) | 0 (0) |
| Lymphedema | 10 (11.1) | 0 (0) | 0 (0) |
| Memory impairment | 10 (11.1) | 0 (0) | 0 (0) |
| Febrile neutropenia | 0 (0) | 1 (1) | 1 (1) |
| AE (N = 90) . | Any grade n (%) . | Grade ≥ 3 n (%) . | Grade 4 n (%) . |
|---|---|---|---|
| Diarrhea | 55 (61.1) | 2 (2.2) | 0 (0) |
| Rash (maculopapular) | 48 (53.3) | 10 (11.1) | 0 (0) |
| Fatigue | 47 (52.2) | 4 (4.4) | 0 (0) |
| Constipation | 44 (48.9) | 0 (0) | 0 (0) |
| Myalgia | 41 (45.6) | 0 (0) | 0 (0) |
| Cough | 30 (33.3) | 2 (2.2) | 0 (0) |
| Nausea | 27 (30) | 0 (0) | 0 (0) |
| Dyspnea | 23 (25.6) | 0 (0) | 0 (0) |
| Upper respiratory infection | 23 (25.6) | 1 (1) | 0 (0) |
| Fever | 21 (23.3) | 1 (1) | 0 (0) |
| Headache | 20 (22.2) | 1 (1) | 0 (0) |
| Neutropenia | 20 (22.2) | 7 (7.8) | 10 (11.1) |
| Allergic rhinitis | 16 (17.8) | 0 (0) | 0 (0) |
| Lower extremity edema | 14 (15.6) | 0 (0) | 0 (0) |
| Dizziness | 13 (14.4) | 0 (0) | 0 (0) |
| Pneumonia | 10 (11.1) | 6 (6.7) | 0 (0) |
| Lymphedema | 10 (11.1) | 0 (0) | 0 (0) |
| Memory impairment | 10 (11.1) | 0 (0) | 0 (0) |
| Febrile neutropenia | 0 (0) | 1 (1) | 1 (1) |