Patient characteristics
| Characteristic (N = 243 patients) . | Value . |
|---|---|
| Median age (range), y | 61 (34-76) |
| Gender, male, n (%) | 146 (60) |
| Race, n (%) | |
| White | 199 (82) |
| Black | 42 (17) |
| Asian/other | 3 (1) |
| R-ISS (n = 237), n (%) | |
| I | 52 (21) |
| II | 164 (69) |
| III | 21 (9) |
| Protocol enrollment, n (%) | |
| TT4 | 142 (58) |
| TT5 | 38 (16) |
| TT6 | 63 (26) |
| GEP70 high risk, n (%) | 35 (14) |
| EMD, n (%) | 12 (5) |
| Translocation t(4;14), n (%) | 28/243 (12) |
| Translocation t(14;16), n (%) | 13/243 (5) |
| Translocation t(11;14), n (%) | 55/243 (23) |
| Gain(1q), n (%) | 84/218 (39) |
| With concomitant other high-risk alteration∗ | 45/84 (54) |
| Amp(1q), n (%) | 33/218 (15) |
| With concomitant other high-risk alteration∗ | 20/33 (60) |
| Del(1p), n (%) | 45/218 (21) |
| Del(17p), n (%) | 29/231 (13) |
| Median follow-up time (IQR), y | 9.9 (6.79-10.80) |
| Characteristic (N = 243 patients) . | Value . |
|---|---|
| Median age (range), y | 61 (34-76) |
| Gender, male, n (%) | 146 (60) |
| Race, n (%) | |
| White | 199 (82) |
| Black | 42 (17) |
| Asian/other | 3 (1) |
| R-ISS (n = 237), n (%) | |
| I | 52 (21) |
| II | 164 (69) |
| III | 21 (9) |
| Protocol enrollment, n (%) | |
| TT4 | 142 (58) |
| TT5 | 38 (16) |
| TT6 | 63 (26) |
| GEP70 high risk, n (%) | 35 (14) |
| EMD, n (%) | 12 (5) |
| Translocation t(4;14), n (%) | 28/243 (12) |
| Translocation t(14;16), n (%) | 13/243 (5) |
| Translocation t(11;14), n (%) | 55/243 (23) |
| Gain(1q), n (%) | 84/218 (39) |
| With concomitant other high-risk alteration∗ | 45/84 (54) |
| Amp(1q), n (%) | 33/218 (15) |
| With concomitant other high-risk alteration∗ | 20/33 (60) |
| Del(1p), n (%) | 45/218 (21) |
| Del(17p), n (%) | 29/231 (13) |
| Median follow-up time (IQR), y | 9.9 (6.79-10.80) |
EMD, extramedullary disease; IQR, interquartile range.
In combination with translocation t14;14, t14;16, del 1p, or del 17p.