Hematological parameters for CSPα−/− mice
| Parameter . | CSPα+/+ . | CSPα+/− . | CSPα−/− . | CSPα+/+ vs CSPα−/− P value . | CSPα+/− vs CSPα−/− P value . | CSPα+/+ vs CSPα+/− P value . |
|---|---|---|---|---|---|---|
| Erythrocytes | ||||||
| Erythrocytes (×106/μL) | 8.06 ± 0.420 | 7.65 ± 0.569 | 8.39 ± 0.786 | >.9999 | .0544 | .4242 |
| MCV (fL) | 50.5 ± 1.23 | 50.7 ± 1.13 | 44.5 ± 1.17 | .0008 | .0005 | >.9999 |
| Hemoglobin (g/dL) | 12.2 ± 0.572 | 11.6 ± 0.643 | 11.3 ± 1.11 | .2736 | >.9999 | .6184 |
| MCH (pg) | 15.1 ± 0.263 | 15.2 ± 0.345 | 13.5 ± 0.289 | .0024 | .0001 | >.9999 |
| MCHC (g/dL) | 29.8 ± 0.625 | 30.1 ± 0.858 | 30.3 ± 0.394 | .3583 | >.9999 | >.9999 |
| Reticulocytes (×103/μL) | 329 ± 38.5 | 369 ± 167 | 481 ± 109 | .0035 | .0218 | >.9999 |
| Platelets | ||||||
| Platelets (×103/μL) | 656 ± 148 | 603 ± 140 | 766 ± 117 | .2950 | .0325 | >.9999 |
| MPV (fL) | 6.56 ± 1.16 | 6.56 ±1.19 | 7.58 ± 0.186 | .6203 | .4264 | >.9999 |
| Leukocytes | ||||||
| WBC (×103/μL) | 10.1 ± 2.83 | 8.95 ± 1.70 | 4.19 ± 1.63 | .0003 | .0038 | >.9999 |
| Neutrophils (×103/μL) | 1.03 ± 1.07 | 0.645 ± 0.319 | 0.983 ± 0.320 | .4339 | .1650 | >.9999 |
| Lymphocytes (×103/μL) | 8.73 ± 1.86 | 7.98 ± 1.61 | 2.97 ± 1.64 | .0003 | .0019 | >.9999 |
| Monocytes (×103/μL) | 0.137 ± 0.127 | 0.186 ± 0.136 | 0.0422 ± 0.0217 | .0217 | .0003 | .6625 |
| Eosinophils (×103/μL) | 0.166 ± 0.0743 | 0.136 ± 0.0606 | 0.182 ± 0.0963 | >.9999 | .4764 | .9708 |
| Basophils (×103/μL) | 0.0140 ± 0.0126 | 0.010 ± 0.00943 | 0.00889 ± 0.0127 | .6495 | >.9999 | >.9999 |
| Parameter . | CSPα+/+ . | CSPα+/− . | CSPα−/− . | CSPα+/+ vs CSPα−/− P value . | CSPα+/− vs CSPα−/− P value . | CSPα+/+ vs CSPα+/− P value . |
|---|---|---|---|---|---|---|
| Erythrocytes | ||||||
| Erythrocytes (×106/μL) | 8.06 ± 0.420 | 7.65 ± 0.569 | 8.39 ± 0.786 | >.9999 | .0544 | .4242 |
| MCV (fL) | 50.5 ± 1.23 | 50.7 ± 1.13 | 44.5 ± 1.17 | .0008 | .0005 | >.9999 |
| Hemoglobin (g/dL) | 12.2 ± 0.572 | 11.6 ± 0.643 | 11.3 ± 1.11 | .2736 | >.9999 | .6184 |
| MCH (pg) | 15.1 ± 0.263 | 15.2 ± 0.345 | 13.5 ± 0.289 | .0024 | .0001 | >.9999 |
| MCHC (g/dL) | 29.8 ± 0.625 | 30.1 ± 0.858 | 30.3 ± 0.394 | .3583 | >.9999 | >.9999 |
| Reticulocytes (×103/μL) | 329 ± 38.5 | 369 ± 167 | 481 ± 109 | .0035 | .0218 | >.9999 |
| Platelets | ||||||
| Platelets (×103/μL) | 656 ± 148 | 603 ± 140 | 766 ± 117 | .2950 | .0325 | >.9999 |
| MPV (fL) | 6.56 ± 1.16 | 6.56 ±1.19 | 7.58 ± 0.186 | .6203 | .4264 | >.9999 |
| Leukocytes | ||||||
| WBC (×103/μL) | 10.1 ± 2.83 | 8.95 ± 1.70 | 4.19 ± 1.63 | .0003 | .0038 | >.9999 |
| Neutrophils (×103/μL) | 1.03 ± 1.07 | 0.645 ± 0.319 | 0.983 ± 0.320 | .4339 | .1650 | >.9999 |
| Lymphocytes (×103/μL) | 8.73 ± 1.86 | 7.98 ± 1.61 | 2.97 ± 1.64 | .0003 | .0019 | >.9999 |
| Monocytes (×103/μL) | 0.137 ± 0.127 | 0.186 ± 0.136 | 0.0422 ± 0.0217 | .0217 | .0003 | .6625 |
| Eosinophils (×103/μL) | 0.166 ± 0.0743 | 0.136 ± 0.0606 | 0.182 ± 0.0963 | >.9999 | .4764 | .9708 |
| Basophils (×103/μL) | 0.0140 ± 0.0126 | 0.010 ± 0.00943 | 0.00889 ± 0.0127 | .6495 | >.9999 | >.9999 |
Results are the means ± standard deviation. Values that are bold indicate a signfinance of P ≤ .05.
MCH, mean corpuscular hemoglobin; MCHC, mean corpuscular hemoglobin concentrations; MCV, mean corpuscular volume; MPV, mean platelet volume; WBC, white blood cells.