Table 7.

Characteristics of patients with major bleeding

VariableStatistics (N = 18)
Age at the time of bleed, median (min, max) 12.3 (0.2, 21.8) 
Days between anticoagulation start date and bleed date, median (min, max) 56 (6, 2336) 
Anticoagulant at the time of bleed, n (%)  
Enoxaparin 11 (61.1) 
Rivaroxaban 5 (27.8) 
UFH 2 (11.1) 
Sex (n = 16), n (%)  
Female 7 (43.8) 
Male 9 (56.2) 
Race (n = 16), n (%)  
Asian 1 (6.3) 
Black 2 (12.5) 
White 12 (75.0) 
Other 1 (6.3) 
Ethnicity (n = 16), n (%)  
Hispanic 1 (6.3) 
Non-Hispanic 15 (93.7) 
Definition of bleed  
Hgb drop >2 gm 11 (61.1) 
Bleeding requiring operative procedure for control 6 (33.3) 
Bleeding into a critical area 5 (27.8) 
In or out of hospital at the time of bleed  
In 13 (76.5) 
Out 4 (23.5) 
Site of bleeding  
Gastrointestinal 10 (55.6) 
Head 1 (5.6) 
Hemoperitoneum 1 (5.6) 
Hemorrhagic cystitis 1 (5.6) 
Oral/gum 1 (5.6) 
Pericardium 1 (5.6) 
Pulmonary 1 (5.6) 
Renal 1 (5.6) 
Thigh hematoma 1 (5.6) 
VariableStatistics (N = 18)
Age at the time of bleed, median (min, max) 12.3 (0.2, 21.8) 
Days between anticoagulation start date and bleed date, median (min, max) 56 (6, 2336) 
Anticoagulant at the time of bleed, n (%)  
Enoxaparin 11 (61.1) 
Rivaroxaban 5 (27.8) 
UFH 2 (11.1) 
Sex (n = 16), n (%)  
Female 7 (43.8) 
Male 9 (56.2) 
Race (n = 16), n (%)  
Asian 1 (6.3) 
Black 2 (12.5) 
White 12 (75.0) 
Other 1 (6.3) 
Ethnicity (n = 16), n (%)  
Hispanic 1 (6.3) 
Non-Hispanic 15 (93.7) 
Definition of bleed  
Hgb drop >2 gm 11 (61.1) 
Bleeding requiring operative procedure for control 6 (33.3) 
Bleeding into a critical area 5 (27.8) 
In or out of hospital at the time of bleed  
In 13 (76.5) 
Out 4 (23.5) 
Site of bleeding  
Gastrointestinal 10 (55.6) 
Head 1 (5.6) 
Hemoperitoneum 1 (5.6) 
Hemorrhagic cystitis 1 (5.6) 
Oral/gum 1 (5.6) 
Pericardium 1 (5.6) 
Pulmonary 1 (5.6) 
Renal 1 (5.6) 
Thigh hematoma 1 (5.6) 

There were 16 patients with bleeding and 18 episodes of major bleeding.

Hgb, hemoglobin; UFH, unfractionated heparin.

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