Table 4.

IgG assessment in patients with MM

n = 3405 
≥1 IgG test, , n (%) 3231 (94.9) 
Number of IgG tests per patient during the follow-up period  
Mean ± SD 29.5 ± 31.1 
Median (IQR) 18.0 (7.0-40.0) 
n (%)  
152 (4.7) 
137 (4.2) 
151 (4.7) 
108 (3.3) 
110 (3.4) 
94 (2.9) 
94 (2.9) 
≥8 2385 (73.8) 
Number of IgG testing per patient per year  
Mean ± SD 6.2 ± 9.4 
Median (IQR) 3.5 (1.6-9.1) 
Number of patients with IgG testing after the date of MM diagnosis, n (%) 2716 (84.1) 
Time from IgG testing to end of follow-up, y  
Mean ± SD 6.4 ± 3.9 
Median (IQR) 6.1 (3.5-9.1) 
Average IgG test result, mg/dL,§ n (%)  
<200 35 (1.1) 
≥200 to <400 339 (10.9) 
≥400 to <500 310 (10.0) 
≥500 to <600 389 (12.6) 
≥600 2026 (65.4) 
Proportion of patients with hypogammaglobulinemia, n (%)  
Any IgG test level <500 mg/dL 2075 (67.0) 
First IgG test level <500 mg/dL 957 (30.9) 
Lowest IgG test result, mg/dL,§ n (%)  
<200 618 (19.9) 
≥200 to <400 1091 (35.2) 
≥400 to <500 366 (11.8) 
≥500 to <600 231 (7.5) 
≥600 793 (25.6) 
n = 3405 
≥1 IgG test, , n (%) 3231 (94.9) 
Number of IgG tests per patient during the follow-up period  
Mean ± SD 29.5 ± 31.1 
Median (IQR) 18.0 (7.0-40.0) 
n (%)  
152 (4.7) 
137 (4.2) 
151 (4.7) 
108 (3.3) 
110 (3.4) 
94 (2.9) 
94 (2.9) 
≥8 2385 (73.8) 
Number of IgG testing per patient per year  
Mean ± SD 6.2 ± 9.4 
Median (IQR) 3.5 (1.6-9.1) 
Number of patients with IgG testing after the date of MM diagnosis, n (%) 2716 (84.1) 
Time from IgG testing to end of follow-up, y  
Mean ± SD 6.4 ± 3.9 
Median (IQR) 6.1 (3.5-9.1) 
Average IgG test result, mg/dL,§ n (%)  
<200 35 (1.1) 
≥200 to <400 339 (10.9) 
≥400 to <500 310 (10.0) 
≥500 to <600 389 (12.6) 
≥600 2026 (65.4) 
Proportion of patients with hypogammaglobulinemia, n (%)  
Any IgG test level <500 mg/dL 2075 (67.0) 
First IgG test level <500 mg/dL 957 (30.9) 
Lowest IgG test result, mg/dL,§ n (%)  
<200 618 (19.9) 
≥200 to <400 1091 (35.2) 
≥400 to <500 366 (11.8) 
≥500 to <600 231 (7.5) 
≥600 793 (25.6) 

Of the 6062 patients with MM, 3405 patients had accessible SPEP test results (as documented in pathology reports, commentary sections of laboratory reports, or discharge summaries).

IgG tests were evaluated based on the available SPEP reports.

All IgG tests identified from the unstructured data were included.

§

For patients with multiple IgG tests, the average value was calculated.

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