Clinical characteristics of the study population
| . | All patients (N = 818) . | Profile 1 (n = 204) . | Profile 2 (n = 209) . | Profile 3 (n = 235) . | Profile 4 (n = 170) . |
|---|---|---|---|---|---|
| Age, mean (±SD), y | 57.2 (±14.5) | 49.3 (±14.3) | 59.5 (±15.0)∗ | 57.9 (±12.4)∗,§ | 62.7 (±12.7)∗,‡ |
| Sex, % (n) | |||||
| Female | 58.3% (447) | 62.3% (127) | 88.5% (185) | 4.68% (11)∗,† | 10.6% (18)∗,† |
| Male | 41.7% (341) | 37.7% (77) | 11.5% (24) | 95.3% (224)∗,† | 89.4% (152)∗,† |
| BMI, mean (±SD) | 28.0 (±5.2) | 28.0 (±6.25) | 28.6 (±5.62)§ | 27.8 (±4.49) | 27.5 (±4.24)∗ |
| DVT extent, % (n) | |||||
| Common femoral vein | 21.8% (178) | 32.4% (66) | 14.4% (30) | 1.28% (3) | 46.5% (79) |
| Femoral vein | 27.8% (227) | 21.1% (43)§ | 21.1% (44)§ | 24.7% (58)§ | 48.2% (82) |
| Popliteal vein | 50.5% (413) | 46.6% (95) | 64.6% (135)∗,§ | 74.0% (174)∗,§ | 5.29% (9) |
| Affected side, % (n) | |||||
| Left | 54.2% (443) | 54.4% (111)§ | 51.2% (107)§ | 43.4% (102)§ | 72.4% (123) |
| Right | 45.4% (371) | 44.1% (90)§ | 48.8% (102)§ | 56.6% (133)§ | 27.1% (46) |
| Bilateral | 0.5% (4) | 1.5% (3) | 0.0% (0) | 0.0% (0) | 0.6% (1) |
| Unprovoked, % (n) | 69.3% (567) | 2.5% (5) | 88.0% (184)∗ | 94.0% (221)∗ | 92.4% (157)∗ |
| Previous contralateral DVT, % (n) | 9.8% (80) | 2.9% (6)‡ | 8.13% (17)‡ | 18.7% (44) | 7.7% (13)‡ |
| Chronic inflammatory disease, % (n) | 4.4% (36) | 4.4% (9) | 1.4% (3)‡ | 8.1% (19)† | 2.9% (5) |
| Diabetes, % (n) | 8.4% (69) | 3.9% (8)§ | 8.6% (18)‡,§ | 2.1% (5)†,§ | 22.4% (38) |
| Joint pain, % (n) | 11.6% (95) | 3.9% (8)†,‡ | 33.5% (70) | 0.4% (1) | 9.4% (16)†,‡ |
| Individualized ECT duration, % (n) | 49.9% (408) | 49.0% (100) | 50.7% (106) | 50.2% (118) | 49.4% (84) |
| Acute phase ECT, % (n) | 78.6% (643) | 72.5% (148)†,‡ | 83.3% (174)∗ | 82.1% (193)∗ | 75.3% (128) |
| . | All patients (N = 818) . | Profile 1 (n = 204) . | Profile 2 (n = 209) . | Profile 3 (n = 235) . | Profile 4 (n = 170) . |
|---|---|---|---|---|---|
| Age, mean (±SD), y | 57.2 (±14.5) | 49.3 (±14.3) | 59.5 (±15.0)∗ | 57.9 (±12.4)∗,§ | 62.7 (±12.7)∗,‡ |
| Sex, % (n) | |||||
| Female | 58.3% (447) | 62.3% (127) | 88.5% (185) | 4.68% (11)∗,† | 10.6% (18)∗,† |
| Male | 41.7% (341) | 37.7% (77) | 11.5% (24) | 95.3% (224)∗,† | 89.4% (152)∗,† |
| BMI, mean (±SD) | 28.0 (±5.2) | 28.0 (±6.25) | 28.6 (±5.62)§ | 27.8 (±4.49) | 27.5 (±4.24)∗ |
| DVT extent, % (n) | |||||
| Common femoral vein | 21.8% (178) | 32.4% (66) | 14.4% (30) | 1.28% (3) | 46.5% (79) |
| Femoral vein | 27.8% (227) | 21.1% (43)§ | 21.1% (44)§ | 24.7% (58)§ | 48.2% (82) |
| Popliteal vein | 50.5% (413) | 46.6% (95) | 64.6% (135)∗,§ | 74.0% (174)∗,§ | 5.29% (9) |
| Affected side, % (n) | |||||
| Left | 54.2% (443) | 54.4% (111)§ | 51.2% (107)§ | 43.4% (102)§ | 72.4% (123) |
| Right | 45.4% (371) | 44.1% (90)§ | 48.8% (102)§ | 56.6% (133)§ | 27.1% (46) |
| Bilateral | 0.5% (4) | 1.5% (3) | 0.0% (0) | 0.0% (0) | 0.6% (1) |
| Unprovoked, % (n) | 69.3% (567) | 2.5% (5) | 88.0% (184)∗ | 94.0% (221)∗ | 92.4% (157)∗ |
| Previous contralateral DVT, % (n) | 9.8% (80) | 2.9% (6)‡ | 8.13% (17)‡ | 18.7% (44) | 7.7% (13)‡ |
| Chronic inflammatory disease, % (n) | 4.4% (36) | 4.4% (9) | 1.4% (3)‡ | 8.1% (19)† | 2.9% (5) |
| Diabetes, % (n) | 8.4% (69) | 3.9% (8)§ | 8.6% (18)‡,§ | 2.1% (5)†,§ | 22.4% (38) |
| Joint pain, % (n) | 11.6% (95) | 3.9% (8)†,‡ | 33.5% (70) | 0.4% (1) | 9.4% (16)†,‡ |
| Individualized ECT duration, % (n) | 49.9% (408) | 49.0% (100) | 50.7% (106) | 50.2% (118) | 49.4% (84) |
| Acute phase ECT, % (n) | 78.6% (643) | 72.5% (148)†,‡ | 83.3% (174)∗ | 82.1% (193)∗ | 75.3% (128) |
Pairwise comparisons of profiles were corrected for multiple testing with a false-discovery rate of 5% (Benjamini-Hochberg method). Bold values indicate significant difference compared with all profiles.
SD, standard deviation.
Indicates significant difference compared with profile 1.
Indicates significant difference compared with profile 2.
Indicates significant difference compared with profile 3.
Indicates significant difference compared with profile 4.