Table 2

Summary statistics per patient-year by hydroxyurea use (current)

VariablenHydroxyurea use this year (n = 6308)No hydroxyurea use this year (n = 5554)P value 
Age (years) 11 925 9.9 (4.5) 6.5 (5.2) <0.001 
Sex 11 924   <0.001 
Female  3089 (49%) 3013 (54%)  
Male  3219 (51%) 2540 (46%)  
MCV (fL) 9744 95.1 (12.2) 83.2 (8.9) <0.001 
Hgb (g/dL) 9738 9.1 (1.2) 9.0 (1.3) <0.001 
ANC (103/μL) 9655 4.5 (1.9) 4.8 (2.4) <0.001 
ED visits per year 11 925 1.1 (1.9) 1.1 (1.7) 0.2 
Hospital days per year 11 925 3.8 (5.7) 2.8 (4.4) <0.001 
Adherence hydroxyurea 4790 2516 (53%) NA NA 
VariablenHydroxyurea use this year (n = 6308)No hydroxyurea use this year (n = 5554)P value 
Age (years) 11 925 9.9 (4.5) 6.5 (5.2) <0.001 
Sex 11 924   <0.001 
Female  3089 (49%) 3013 (54%)  
Male  3219 (51%) 2540 (46%)  
MCV (fL) 9744 95.1 (12.2) 83.2 (8.9) <0.001 
Hgb (g/dL) 9738 9.1 (1.2) 9.0 (1.3) <0.001 
ANC (103/μL) 9655 4.5 (1.9) 4.8 (2.4) <0.001 
ED visits per year 11 925 1.1 (1.9) 1.1 (1.7) 0.2 
Hospital days per year 11 925 3.8 (5.7) 2.8 (4.4) <0.001 
Adherence hydroxyurea 4790 2516 (53%) NA NA 

Unit of analysis for this table is individual person-year, where year is by age.

Mean (standard deviation [sd]) for continuous variables; N (%) for categorical variables.

ANC, absolute neutrophil count; ED, emergency department; Hgb, hemoglobin; MCV, mean corpuscular volume.

Wilcoxon rank sum test; Pearson's Chi-squared test; Fisher's exact test.

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