Table 3.

Causes of death and types of histologic transformation

DR, n = 30DE, n = 65
Death, n 19 16 
Causes of death, n (%)   
CLL 8 (42.1) 1 (6.3) 
Histologic transformation 5 (26.3) 3 (18.8) 
Infection 2 (10.5)  4 (25.0) 
Bleeding 1 (5.3) 0 (0.0) 
Second cancer 1 (5.3)  2 (12.5)  
Other 0 (0.0) 3 (18.8)§  
Unknown 2 (10.5) 3 (18.8) 
Histologic transformation, n 
Types of transformation, n (%)   
DLBCL 8 (26.7) 4 (6.2) 
Histiocytic sarcoma 1 (3.3) 0 (0.0) 
DR, n = 30DE, n = 65
Death, n 19 16 
Causes of death, n (%)   
CLL 8 (42.1) 1 (6.3) 
Histologic transformation 5 (26.3) 3 (18.8) 
Infection 2 (10.5)  4 (25.0) 
Bleeding 1 (5.3) 0 (0.0) 
Second cancer 1 (5.3)  2 (12.5)  
Other 0 (0.0) 3 (18.8)§  
Unknown 2 (10.5) 3 (18.8) 
Histologic transformation, n 
Types of transformation, n (%)   
DLBCL 8 (26.7) 4 (6.2) 
Histiocytic sarcoma 1 (3.3) 0 (0.0) 

DLBCL, diffuse large B-cell lymphoma.

Fungal infection for both patients.

Metastatic lung cancer.

Treatment-related myeloid neoplasms for both patients.

§

Heart failure, multiorgan failure, and small bowel obstruction in one patient each.

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