Cytogenetic and molecular features of patients with B-ALL analyzed in this study
| . | Total no. of patients . | Age, y . |
|---|---|---|
| Pediatric B-ALL | ||
| Diagnosis | 32 | |
| Cytogenetics | ||
| Hyperdiploid | 6 | 5.5 ± 1.6 |
| ETV6::RUNX1 | 10 | 4.9 ± 1.1 |
| iAMP21 | 3 | 7.8 ± 2.7 |
| KMT2A::AFF1 | 5 | 0.8 ± 0.1 |
| TCF3::PBX1 | 1 | 9.0 |
| B-other | 6 | 9.0 ± 2.7 |
| NA | 1 | — |
| Sex | ||
| Male | 16 | 6.1 ± 4.3 |
| Female | 10 | 6.8 ± 1.5 |
| NA | 6 | — |
| Relapse | 25 | |
| Cytogenetics | ||
| Hyperdiploid | 2 | 9.3 ± 4.3 |
| ETV6::RUNX1 | 1 | 5.5 |
| iAMP21 | 3 | 11.2 ± 2.9 |
| KMT2A::AFF1 | 2 | 4.5 ± 0.5 |
| TCF3::PBX1 | 6 | 15.6 ± 1.9 |
| B-other | 1 | 3 |
| NA | 10 | — |
| Sex | ||
| Male | 10 | 8.1 ± 2.1 |
| Female | 7 | 11.2 ± 2.1 |
| NA | 8 | — |
| Allotransplanted | ||
| Yes | 4 | 8.8 ± 2.8 |
| No | 6 | 11.0 ± 2.5 |
| NA | 15 | — |
| Adult B-ALL | ||
| Diagnosis | 15 | |
| Cytogenetics | ||
| BCR-ABL+ | 3 | 41.7 ± 5.0 |
| BCR-ABL– | 10 | 39.1 ± 6.0 |
| NA | 2 | 22.5 ± 0.5 |
| Sex | ||
| Male | 7 | 39.0 ± 6.8 |
| Female | 8 | 36.0 ± 5.8 |
| Relapse | 13 | |
| Cytogenetics | ||
| BCR-ABL– | 11 | 39.6 ± 5.4 |
| NA | 2 | 43.5 ± 10.5 |
| Sex | ||
| Male | 8 | 38.2 ± 3.7 |
| Female | 5 | 43.4 ± 11.8 |
| Allotransplanted | ||
| Yes | 1 | 33.0 |
| No | 5 | 40.6 ± 6.7 |
| NA | 7 | — |
| . | Total no. of patients . | Age, y . |
|---|---|---|
| Pediatric B-ALL | ||
| Diagnosis | 32 | |
| Cytogenetics | ||
| Hyperdiploid | 6 | 5.5 ± 1.6 |
| ETV6::RUNX1 | 10 | 4.9 ± 1.1 |
| iAMP21 | 3 | 7.8 ± 2.7 |
| KMT2A::AFF1 | 5 | 0.8 ± 0.1 |
| TCF3::PBX1 | 1 | 9.0 |
| B-other | 6 | 9.0 ± 2.7 |
| NA | 1 | — |
| Sex | ||
| Male | 16 | 6.1 ± 4.3 |
| Female | 10 | 6.8 ± 1.5 |
| NA | 6 | — |
| Relapse | 25 | |
| Cytogenetics | ||
| Hyperdiploid | 2 | 9.3 ± 4.3 |
| ETV6::RUNX1 | 1 | 5.5 |
| iAMP21 | 3 | 11.2 ± 2.9 |
| KMT2A::AFF1 | 2 | 4.5 ± 0.5 |
| TCF3::PBX1 | 6 | 15.6 ± 1.9 |
| B-other | 1 | 3 |
| NA | 10 | — |
| Sex | ||
| Male | 10 | 8.1 ± 2.1 |
| Female | 7 | 11.2 ± 2.1 |
| NA | 8 | — |
| Allotransplanted | ||
| Yes | 4 | 8.8 ± 2.8 |
| No | 6 | 11.0 ± 2.5 |
| NA | 15 | — |
| Adult B-ALL | ||
| Diagnosis | 15 | |
| Cytogenetics | ||
| BCR-ABL+ | 3 | 41.7 ± 5.0 |
| BCR-ABL– | 10 | 39.1 ± 6.0 |
| NA | 2 | 22.5 ± 0.5 |
| Sex | ||
| Male | 7 | 39.0 ± 6.8 |
| Female | 8 | 36.0 ± 5.8 |
| Relapse | 13 | |
| Cytogenetics | ||
| BCR-ABL– | 11 | 39.6 ± 5.4 |
| NA | 2 | 43.5 ± 10.5 |
| Sex | ||
| Male | 8 | 38.2 ± 3.7 |
| Female | 5 | 43.4 ± 11.8 |
| Allotransplanted | ||
| Yes | 1 | 33.0 |
| No | 5 | 40.6 ± 6.7 |
| NA | 7 | — |
NA, not available.