Number of transplant procedures for nonclassical MPNs and MDS/MPNs performed in Europe from 2016 to 2023
| Diagnosis . | Year of HCT . | 2016 Frequency . | 2017 Frequency . | 2018 Frequency . | 2019 Frequency . | 2020 Frequency . | 2021 Frequency . | 2022 Frequency . | 2023 Frequency . |
|---|---|---|---|---|---|---|---|---|---|
| MPN | CNL (WHO/ICC) | 4 | 7 | 11 | 9 | 13 | 8 | 10 | 10 |
| CEL (WHO)/CEL, NOS (ICC) | 1 | 1 | 4 | — | 2 | 1 | 3 | 4 | |
| MLN-TK with ABL1 rearrangement | — | — | — | — | — | — | — | — | |
| MLN-TK with FGFR1 rearrangement | 2 | 3 | 5 | 1 | 3 | 2 | — | 1 | |
| MLN-TK with FLT3 rearrangement | — | — | — | — | — | — | — | — | |
| MLN-TK with JAK2 rearrangements | — | — | — | — | — | 1 | 1 | 4 | |
| MLN-TK with PDGFRA/B rearrangement | — | — | — | — | — | — | — | 1 | |
| MPN, NOS (WHO)/ MPN-U (ICC) | 37 | 35 | 37 | 46 | 42 | 46 | 42 | 80 | |
| Total nonclassical MPN | 44 | 46 | 57 | 56 | 60 | 58 | 56 | 100 | |
| MDS/MPN | MDS/MPN with neutrophilia (WHO)/aCML (ICC) | 37 | 32 | 40 | 44 | 36 | 40 | 38 | 40 |
| MDS/MPN with ring sideroblasts and thrombocytosis, NOS (ICC only) | — | — | — | — | — | 1 | 2 | 7 | |
| MDS/MPN with SF3B1 mutation and thrombocytosis (WHO)/MDS/MPN with thrombocytosis and SF3B1 mutation (ICC) | — | — | — | — | — | — | — | — | |
| MDS/MPN, NOS (WHO/ICC) | 59 | 84 | 98 | 91 | 107 | 99 | 112 | 86 | |
| Total nonclassical MDS/MPN | 96 | 116 | 138 | 135 | 143 | 140 | 152 | 133 |
| Diagnosis . | Year of HCT . | 2016 Frequency . | 2017 Frequency . | 2018 Frequency . | 2019 Frequency . | 2020 Frequency . | 2021 Frequency . | 2022 Frequency . | 2023 Frequency . |
|---|---|---|---|---|---|---|---|---|---|
| MPN | CNL (WHO/ICC) | 4 | 7 | 11 | 9 | 13 | 8 | 10 | 10 |
| CEL (WHO)/CEL, NOS (ICC) | 1 | 1 | 4 | — | 2 | 1 | 3 | 4 | |
| MLN-TK with ABL1 rearrangement | — | — | — | — | — | — | — | — | |
| MLN-TK with FGFR1 rearrangement | 2 | 3 | 5 | 1 | 3 | 2 | — | 1 | |
| MLN-TK with FLT3 rearrangement | — | — | — | — | — | — | — | — | |
| MLN-TK with JAK2 rearrangements | — | — | — | — | — | 1 | 1 | 4 | |
| MLN-TK with PDGFRA/B rearrangement | — | — | — | — | — | — | — | 1 | |
| MPN, NOS (WHO)/ MPN-U (ICC) | 37 | 35 | 37 | 46 | 42 | 46 | 42 | 80 | |
| Total nonclassical MPN | 44 | 46 | 57 | 56 | 60 | 58 | 56 | 100 | |
| MDS/MPN | MDS/MPN with neutrophilia (WHO)/aCML (ICC) | 37 | 32 | 40 | 44 | 36 | 40 | 38 | 40 |
| MDS/MPN with ring sideroblasts and thrombocytosis, NOS (ICC only) | — | — | — | — | — | 1 | 2 | 7 | |
| MDS/MPN with SF3B1 mutation and thrombocytosis (WHO)/MDS/MPN with thrombocytosis and SF3B1 mutation (ICC) | — | — | — | — | — | — | — | — | |
| MDS/MPN, NOS (WHO/ICC) | 59 | 84 | 98 | 91 | 107 | 99 | 112 | 86 | |
| Total nonclassical MDS/MPN | 96 | 116 | 138 | 135 | 143 | 140 | 152 | 133 |