Unadjusted mean baseline scores of psychological distress, PTSD, symptom burden, and fatigue among 467 adults with MGUS or SMM
| . | Total N (%) or mean (SD) . | MGUS Mean score (SD) . | SMM Mean score (SD) . |
|---|---|---|---|
| Overall | 467 (100%) | 284 (60.8%) | 183 (39.2%) |
| HADS,∗ total score, mean (SD) | 9.2 (6.4) | 9.5 (6.5) | 8.7 (6.1) |
| HADS: anxiety, mean (SD) | 5.5 (3.8) | 5.6 (3.8) | 5.3 (3.9) |
| <8 | 342 (73%) | 3.7 (2.1) | 3.6 (2.3) |
| ≥8 | 125 (27%) | 10.5 (2.7) | 10.7 (2.5) |
| HADS: depression, mean (SD) | 3.7 (3.3) | 3.9 (3.4) | 3.4 (3.0) |
| <8 | 403 (86%) | 2.8 (2.2) | 2.6 (2.2) |
| ≥8 | 64 (14%) | 10.2 (2.0) | 9.2 (1.8) |
| PCL-C† score, mean (SD) | 27.2 (11.6) | 27.3 (12.1) | 27.1 (10.8) |
| <33 | 356 (76%) | 21.5 (5.2) | 22.2 (4.1) |
| ≥33 | 111 (24%) | 44.8 (10.0) | 44.0 (9.7) |
| ESAS-r‡ score, mean (SD) | 18.5 (16.8) | 19.6 (17.8) | 16.6 (14.8) |
| Scored <7 on each item | 324 (69%) | 11.0 (10.0) | 10.3 (8.5) |
| Scored ≥7 on at least 1 item | 143 (31%) | 38.4 (16.6) | 31.9 (15.6) |
| FACIT-F§ score, mean (SD) | 38.3 (11.1) | 37.6 (11.6) | 39.5 (10.3) |
| ≥30 | 366 (78%) | 42.8 (6.5) | 43.4 (6.1) |
| <30 | 98 (21%) | 20.0 (6.5) | 21.8 (5.7) |
| . | Total N (%) or mean (SD) . | MGUS Mean score (SD) . | SMM Mean score (SD) . |
|---|---|---|---|
| Overall | 467 (100%) | 284 (60.8%) | 183 (39.2%) |
| HADS,∗ total score, mean (SD) | 9.2 (6.4) | 9.5 (6.5) | 8.7 (6.1) |
| HADS: anxiety, mean (SD) | 5.5 (3.8) | 5.6 (3.8) | 5.3 (3.9) |
| <8 | 342 (73%) | 3.7 (2.1) | 3.6 (2.3) |
| ≥8 | 125 (27%) | 10.5 (2.7) | 10.7 (2.5) |
| HADS: depression, mean (SD) | 3.7 (3.3) | 3.9 (3.4) | 3.4 (3.0) |
| <8 | 403 (86%) | 2.8 (2.2) | 2.6 (2.2) |
| ≥8 | 64 (14%) | 10.2 (2.0) | 9.2 (1.8) |
| PCL-C† score, mean (SD) | 27.2 (11.6) | 27.3 (12.1) | 27.1 (10.8) |
| <33 | 356 (76%) | 21.5 (5.2) | 22.2 (4.1) |
| ≥33 | 111 (24%) | 44.8 (10.0) | 44.0 (9.7) |
| ESAS-r‡ score, mean (SD) | 18.5 (16.8) | 19.6 (17.8) | 16.6 (14.8) |
| Scored <7 on each item | 324 (69%) | 11.0 (10.0) | 10.3 (8.5) |
| Scored ≥7 on at least 1 item | 143 (31%) | 38.4 (16.6) | 31.9 (15.6) |
| FACIT-F§ score, mean (SD) | 38.3 (11.1) | 37.6 (11.6) | 39.5 (10.3) |
| ≥30 | 366 (78%) | 42.8 (6.5) | 43.4 (6.1) |
| <30 | 98 (21%) | 20.0 (6.5) | 21.8 (5.7) |
Entries that do not sum to 467 exclude missing data.
ESAS-r, Edmonton Symptom Assessment System Revised; FACIT-F, functional assessment of chronic illness therapy: fatigue; PCL-C, posttraumatic stress disorder checklist: civilian version; SD, standard deviation.
HADS, a cutoff of ≥8 indicates clinically significant anxiety or depression.
PCL-C, a cutoff of 33 indicates clinically significant PTSD.
ESAS-r, researchers often use items with scores of ≥7 as may be “severe.”
FACIT-F, a lower score represents higher fatigue; a score <30 indicates severe fatigue.