Primary and secondary outcomes
. | Unpaired analysis . | Paired analysis . | ||||||
---|---|---|---|---|---|---|---|---|
CSP n = 9 . | RSP n = 9 . | Difference . | P value . | CSP n = 8 . | RSP n = 8 . | Difference . | P value . | |
Primary outcome | ||||||||
ASA VerifyNow 1 h, mean ARU (95% CI) | 472 (420-525) | 576 (531-621) | −104 (−168 to −40) | .003 | 463 (407-519) | 569 (520-618) | −106 (−174 to −38) | .02 |
Unpaired analysis | Paired analysis | |||||||
CSP n = 8 | RSP n = 9 | Difference | Pvalue | CSP n = 7 | RSP n = 7 | Difference | Pvalue | |
Secondary outcomes | ||||||||
ASA VerifyNow 4 h, mean ARU (95% CI) | 486 (444-528) | 497 (440-553) | −11 (−54 to 34) | .73 | 487 (437-537) | 495 (422-568) | −8 (−87 to 71) | .82 |
CSP n = 9 | RSP n = 9 | Difference | Pvalue | CSP n = 8 | RSP n = 8 | Difference | Pvalue | |
ASA VerifyNow 24 h, mean ARU (95% CI) | 462 (433-491) | 549 (477-620) | −87 (−158 to −16) | .02 | 462 (428-496) | 538 (460-616) | −76 (−153 to 1) | .06 |
. | Unpaired analysis . | Paired analysis . | ||||||
---|---|---|---|---|---|---|---|---|
CSP n = 9 . | RSP n = 9 . | Difference . | P value . | CSP n = 8 . | RSP n = 8 . | Difference . | P value . | |
Primary outcome | ||||||||
ASA VerifyNow 1 h, mean ARU (95% CI) | 472 (420-525) | 576 (531-621) | −104 (−168 to −40) | .003 | 463 (407-519) | 569 (520-618) | −106 (−174 to −38) | .02 |
Unpaired analysis | Paired analysis | |||||||
CSP n = 8 | RSP n = 9 | Difference | Pvalue | CSP n = 7 | RSP n = 7 | Difference | Pvalue | |
Secondary outcomes | ||||||||
ASA VerifyNow 4 h, mean ARU (95% CI) | 486 (444-528) | 497 (440-553) | −11 (−54 to 34) | .73 | 487 (437-537) | 495 (422-568) | −8 (−87 to 71) | .82 |
CSP n = 9 | RSP n = 9 | Difference | Pvalue | CSP n = 8 | RSP n = 8 | Difference | Pvalue | |
ASA VerifyNow 24 h, mean ARU (95% CI) | 462 (433-491) | 549 (477-620) | −87 (−158 to −16) | .02 | 462 (428-496) | 538 (460-616) | −76 (−153 to 1) | .06 |
Primary outcomes defined as reversal of ASA, 1 hour after transfusion; and secondary outcomes are defined as reversal of ASA, 4 and 24 hours after transfusion.
CI, confidence interval.