Unadjusted and adjusted analyses of factors associated with QOL
| . | QOL . | Unadjusted . | Adjusted, n = 191 . | |||||
|---|---|---|---|---|---|---|---|---|
| n . | Mean (SD) . | Mean difference . | 95% CI . | P value . | Mean difference . | 95% CI . | P value . | |
| Clinically significant anxiety | <.001 | .71 | ||||||
| Anxiety symptoms absent (HADS-A, <8) | 96 | 74.7 (19.7) | — | — | — | — | ||
| Anxiety symptoms present (HADS-A, ≥8) | 104 | 62.4 (20.4) | −12.3 | −17.9 to −6.7 | −1.1 | −6.6 to 4.5 | ||
| Clinically significant depression | <.001 | <.001 | ||||||
| Depression symptoms absent (HADS-D, <8) | 145 | 75.1 (18.3) | — | — | — | — | ||
| Depression symptoms present (HADS-D, ≥8) | 55 | 50.6 (16.7) | −24.5 | −30.0 to −18.9 | −22.0 | −28.1 to −15.9 | ||
| Age group, y | .32 | |||||||
| ≥60 | 111 | 67 (20.7) | — | — | ||||
| <60 | 89 | 69.9 (21.3) | 3.0 | −2.9 to 8.8 | ||||
| Gender identity | .54 | |||||||
| Not female | 109 | 69.1 (19.4) | — | — | ||||
| Female | 91 | 67.3 (22.7) | −1.8 | −7.7 to 4.0 | ||||
| Marital status | .52 | |||||||
| Married/living with partner | 148 | 68.9 (20.9) | — | — | ||||
| Other | 52 | 66.7 (21.3) | −2.2 | −8.9 to 4.5 | ||||
| Highest level of education achieved | .83 | |||||||
| Bachelor degree or higher | 127 | 68.1 (19.5) | — | — | ||||
| Less than Bachelor degree | 73 | 68.7 (23.3) | 0.7 | −5.4 to 6.7 | ||||
| Religion/spiritual practice | .040 | .006 | ||||||
| Has a religion/spiritual practice | 161 | 69.8 (21) | — | — | — | — | ||
| No religion/spiritual practice | 39 | 62.2 (19.8) | −7.6 | −14.9 to −0.3 | −8.5 | −14.7 to −2.4 | ||
| Race | .070 | |||||||
| White | 170 | 69.4 (20.7) | — | — | ||||
| Non-White | 30 | 61.9 (21.7) | −7.5 | −15.6 to 0.6 | ||||
| Ethnicity | .91 | |||||||
| Not Hispanic or Latinx | 188 | 68.2 (21) | — | — | ||||
| Hispanic or Latinx | 11 | 67.4 (19.9) | −0.8 | −13.5 to 12.0 | ||||
| Monthly household income, $ | .090 | |||||||
| ≥7000 | 88 | 70.5 (20) | — | — | ||||
| <7000 | 98 | 65.4 (21.4) | −5.2 | −11.2 to 0.8 | ||||
| Family finances at end of month∗ | .003 | |||||||
| Some money left over | 126 | 71.6 (19.9) | — | — | ||||
| Just enough/not enough money left over | 64 | 62.3 (21.5) | −9.3 | −15.4 to −3.1 | ||||
| Satisfaction with family finances | <.001 | .004 | ||||||
| Completely/very satisfied | 102 | 74.5 (18.7) | — | — | — | — | ||
| Moderately/slightly/not satisfied | 93 | 61.4 (21.2) | −13.1 | −18.7 to −7.5 | −7.7 | −12.9 to −2.4 | ||
| Social support score | .002 | .97 | ||||||
| Greater than median (higher levels of support) | 100 | 72.6 (20.2) | — | — | — | — | ||
| Less than or equal to median (lower levels of support) | 99 | 63.7 (20.7) | −8.8 | −14.5 to −3.1 | 0.1 | −5.1 to 5.3 | ||
| Chemotherapy started before study consent | .28 | |||||||
| Yes | 75 | 66.6 (19.1) | — | — | ||||
| No | 123 | 69.9 (21.8) | 3.3 | −2.7 to 9.3 | ||||
| Medical mistrust score | .045 | .44 | ||||||
| Greater than median (lower levels of mistrust) | 87 | 71.6 (20.8) | — | — | — | — | ||
| Less than or equal to median (higher levels of mistrust) | 112 | 65.6 (20.8) | −6.0 | −11.8 to −0.1 | −2.0 | −7.2 to 3.1 | ||
| . | QOL . | Unadjusted . | Adjusted, n = 191 . | |||||
|---|---|---|---|---|---|---|---|---|
| n . | Mean (SD) . | Mean difference . | 95% CI . | P value . | Mean difference . | 95% CI . | P value . | |
| Clinically significant anxiety | <.001 | .71 | ||||||
| Anxiety symptoms absent (HADS-A, <8) | 96 | 74.7 (19.7) | — | — | — | — | ||
| Anxiety symptoms present (HADS-A, ≥8) | 104 | 62.4 (20.4) | −12.3 | −17.9 to −6.7 | −1.1 | −6.6 to 4.5 | ||
| Clinically significant depression | <.001 | <.001 | ||||||
| Depression symptoms absent (HADS-D, <8) | 145 | 75.1 (18.3) | — | — | — | — | ||
| Depression symptoms present (HADS-D, ≥8) | 55 | 50.6 (16.7) | −24.5 | −30.0 to −18.9 | −22.0 | −28.1 to −15.9 | ||
| Age group, y | .32 | |||||||
| ≥60 | 111 | 67 (20.7) | — | — | ||||
| <60 | 89 | 69.9 (21.3) | 3.0 | −2.9 to 8.8 | ||||
| Gender identity | .54 | |||||||
| Not female | 109 | 69.1 (19.4) | — | — | ||||
| Female | 91 | 67.3 (22.7) | −1.8 | −7.7 to 4.0 | ||||
| Marital status | .52 | |||||||
| Married/living with partner | 148 | 68.9 (20.9) | — | — | ||||
| Other | 52 | 66.7 (21.3) | −2.2 | −8.9 to 4.5 | ||||
| Highest level of education achieved | .83 | |||||||
| Bachelor degree or higher | 127 | 68.1 (19.5) | — | — | ||||
| Less than Bachelor degree | 73 | 68.7 (23.3) | 0.7 | −5.4 to 6.7 | ||||
| Religion/spiritual practice | .040 | .006 | ||||||
| Has a religion/spiritual practice | 161 | 69.8 (21) | — | — | — | — | ||
| No religion/spiritual practice | 39 | 62.2 (19.8) | −7.6 | −14.9 to −0.3 | −8.5 | −14.7 to −2.4 | ||
| Race | .070 | |||||||
| White | 170 | 69.4 (20.7) | — | — | ||||
| Non-White | 30 | 61.9 (21.7) | −7.5 | −15.6 to 0.6 | ||||
| Ethnicity | .91 | |||||||
| Not Hispanic or Latinx | 188 | 68.2 (21) | — | — | ||||
| Hispanic or Latinx | 11 | 67.4 (19.9) | −0.8 | −13.5 to 12.0 | ||||
| Monthly household income, $ | .090 | |||||||
| ≥7000 | 88 | 70.5 (20) | — | — | ||||
| <7000 | 98 | 65.4 (21.4) | −5.2 | −11.2 to 0.8 | ||||
| Family finances at end of month∗ | .003 | |||||||
| Some money left over | 126 | 71.6 (19.9) | — | — | ||||
| Just enough/not enough money left over | 64 | 62.3 (21.5) | −9.3 | −15.4 to −3.1 | ||||
| Satisfaction with family finances | <.001 | .004 | ||||||
| Completely/very satisfied | 102 | 74.5 (18.7) | — | — | — | — | ||
| Moderately/slightly/not satisfied | 93 | 61.4 (21.2) | −13.1 | −18.7 to −7.5 | −7.7 | −12.9 to −2.4 | ||
| Social support score | .002 | .97 | ||||||
| Greater than median (higher levels of support) | 100 | 72.6 (20.2) | — | — | — | — | ||
| Less than or equal to median (lower levels of support) | 99 | 63.7 (20.7) | −8.8 | −14.5 to −3.1 | 0.1 | −5.1 to 5.3 | ||
| Chemotherapy started before study consent | .28 | |||||||
| Yes | 75 | 66.6 (19.1) | — | — | ||||
| No | 123 | 69.9 (21.8) | 3.3 | −2.7 to 9.3 | ||||
| Medical mistrust score | .045 | .44 | ||||||
| Greater than median (lower levels of mistrust) | 87 | 71.6 (20.8) | — | — | — | — | ||
| Less than or equal to median (higher levels of mistrust) | 112 | 65.6 (20.8) | −6.0 | −11.8 to −0.1 | −2.0 | −7.2 to 3.1 | ||
Mean differences (ie, β coefficients) from univariable and multivariable linear regression; mean differences of >0 correspond to better QOL.
Only 7 of 64 participants with “just enough” or “not enough money left over” at the end of the month were completely/very satisfied with their family finances. Because of this overlap, “satisfaction with family finances” was included in the multivariable model, whereas “family finances at end of the month” was not included in the model.