Table 3.

Unadjusted and adjusted analyses of factors associated with clinically significant depression

Characteristic UnadjustedAdjusted, n = 192
Depression symptoms present (HADS-D ≥ 8)
n = 55
Depression symptoms absent (HADS-D < 8)
n = 145
P valueOR95% CIP value
Age group, y   .88    
≥60 31 (27.9%) 80 (72.1%)     
<60 24 (27.0%) 65 (73.0%)     
Gender identity   >.99    
Not female 30 (27.5%) 79 (72.5%)     
Female 25 (27.5%) 66 (72.5%)     
Marital status   .54    
Married/living with partner 39 (26.4%) 109 (73.6%)     
Other 16 (30.8%) 36 (69.2%)     
Highest level of education achieved   .72    
Bachelor degree or higher 36 (28.3%) 91 (71.7%)     
Less than Bachelor degree 19 (26.0%) 54 (74.0%)     
Religion/spiritual practice   .49    
Has a religion/spiritual practice 46 (28.6%) 115 (71.4%)     
No religion/spiritual practice 9 (23.1%) 30 (76.9%)     
Race   .22    
White 44 (25.9%) 126 (74.1%)     
Non-White 11 (36.7%) 19 (63.3%)     
Ethnicity   .30    
Not Hispanic or Latinx 54 (28.7%) 134 (71.3%)     
Hispanic or Latinx 1 (9.1%) 10 (90.9%)     
Monthly household income, $   .77    
≥7000 25 (28.4%) 63 (71.6%)     
<7000 26 (26.5%) 72 (73.5%)     
Family finances at end of month    .61    
Some money left over 33 (26.2%) 93 (73.8%)     
Just enough/not enough money left over 19 (29.7%) 45 (70.3%)     
Satisfaction with family finances   .002   .032 
Completely/very satisfied 18 (17.6%) 84 (82.4%)  — —  
Moderately/slightly/not satisfied 35 (37.6%) 58 (62.4%)  2.12 1.07-4.30  
Social support score   <.001   .003 
Greater than median (higher levels of support) 15 (15.0%) 85 (85.0%)  — —  
Less than or equal to median (lower levels of support) 40 (40.4%) 59 (59.6%)  2.88 1.43-6.00  
Chemotherapy started before study consent   .98    
Yes 20 (26.7%) 55 (73.3%)     
No 33 (26.8%) 90 (73.2%)     
Medical mistrust score   .024   .20 
Greater than median (lower levels of mistrust) 17 (19.5%) 70 (80.5%)  — —  
Less than or equal to median (higher levels of mistrust) 38 (33.9%) 74 (66.1%)  1.58 0.79-3.25  
Characteristic UnadjustedAdjusted, n = 192
Depression symptoms present (HADS-D ≥ 8)
n = 55
Depression symptoms absent (HADS-D < 8)
n = 145
P valueOR95% CIP value
Age group, y   .88    
≥60 31 (27.9%) 80 (72.1%)     
<60 24 (27.0%) 65 (73.0%)     
Gender identity   >.99    
Not female 30 (27.5%) 79 (72.5%)     
Female 25 (27.5%) 66 (72.5%)     
Marital status   .54    
Married/living with partner 39 (26.4%) 109 (73.6%)     
Other 16 (30.8%) 36 (69.2%)     
Highest level of education achieved   .72    
Bachelor degree or higher 36 (28.3%) 91 (71.7%)     
Less than Bachelor degree 19 (26.0%) 54 (74.0%)     
Religion/spiritual practice   .49    
Has a religion/spiritual practice 46 (28.6%) 115 (71.4%)     
No religion/spiritual practice 9 (23.1%) 30 (76.9%)     
Race   .22    
White 44 (25.9%) 126 (74.1%)     
Non-White 11 (36.7%) 19 (63.3%)     
Ethnicity   .30    
Not Hispanic or Latinx 54 (28.7%) 134 (71.3%)     
Hispanic or Latinx 1 (9.1%) 10 (90.9%)     
Monthly household income, $   .77    
≥7000 25 (28.4%) 63 (71.6%)     
<7000 26 (26.5%) 72 (73.5%)     
Family finances at end of month    .61    
Some money left over 33 (26.2%) 93 (73.8%)     
Just enough/not enough money left over 19 (29.7%) 45 (70.3%)     
Satisfaction with family finances   .002   .032 
Completely/very satisfied 18 (17.6%) 84 (82.4%)  — —  
Moderately/slightly/not satisfied 35 (37.6%) 58 (62.4%)  2.12 1.07-4.30  
Social support score   <.001   .003 
Greater than median (higher levels of support) 15 (15.0%) 85 (85.0%)  — —  
Less than or equal to median (lower levels of support) 40 (40.4%) 59 (59.6%)  2.88 1.43-6.00  
Chemotherapy started before study consent   .98    
Yes 20 (26.7%) 55 (73.3%)     
No 33 (26.8%) 90 (73.2%)     
Medical mistrust score   .024   .20 
Greater than median (lower levels of mistrust) 17 (19.5%) 70 (80.5%)  — —  
Less than or equal to median (higher levels of mistrust) 38 (33.9%) 74 (66.1%)  1.58 0.79-3.25  

ORs from multivariable logistic regression; ORs of >1 corresponding to increased odds of having clinically significant depression present.

Percentages are row percentages. Frequency counts do not sum to column totals due to missing data as follows: ethnicity (depression absent, n = 1); monthly household income (depression present, n = 4; depression absent, n = 10); family finances at end of month (depression present, n = 3; depression absent, n = 7); satisfaction with family finances (depression present, n = 2; depression absent, n = 3); social support score (depression absent, n = 1); chemotherapy status at study consent (depression present, n = 2); and medical mistrust score (depression absent, n = 1).

Only 7 of 64 participants with “just enough” or “not enough money left over” at the end of the month were completely/very satisfied with their family finances. Because of this overlap, “satisfaction with family finances” was included in the multivariable model, whereas “family finances at end of the month” was not included in the model.

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