Table 2.

Unadjusted and adjusted analyses of factors associated with clinically significant anxiety

Characteristic UnadjustedAdjusted, n = 192
Anxiety symptoms present (HADS-A ≥ 8)
n = 104
Anxiety symptoms absent (HADS-A < 8)
n = 96
P valueOR95% CIP value
Age group, y   <.001   .010 
≥60 45 (40.5%) 66 (59.5%)  — —  
<60 59 (66.3%) 30 (33.7%)  2.36 1.23-4.59  
Gender identity   .014   .026 
Not female 48 (44.0%) 61 (56.0%)  — —  
Female 56 (61.5%) 35 (38.5%)  2.11 1.09-4.14  
Marital status   .001   .14 
Married/living with partner 67 (45.3%) 81 (54.7%)  — —  
Other 37 (71.2%) 15 (28.8%)  1.78 0.83-3.95  
Highest level of education achieved   .55    
Bachelor degree or higher 64 (50.4%) 63 (49.6%)     
Less than bachelor degree 40 (54.8%) 33 (45.2%)     
Religion/spiritual practice   .18    
Has a religion/spiritual practice 80 (49.7%) 81 (50.3%)     
No religion/spiritual practice 24 (61.5%) 15 (38.5%)     
Race   .87    
White 88 (51.8%) 82 (48.2%)     
Non-White 16 (53.3%) 14 (46.7%)     
Ethnicity   .44    
Not Hispanic or Latinx 97 (51.6%) 91 (48.4%)     
Hispanic or Latinx 7 (63.6%) 4 (36.4%)     
Monthly household income, $   .15    
≥7000 42 (47.7%) 46 (52.3%)     
<7000 57 (58.2%) 41 (41.8%)     
Family finances at end of month    .014    
Some money left over 59 (46.8%) 67 (53.2%)     
Just enough/not enough money left over 42 (65.6%) 22 (34.4%)     
Satisfaction with family finances   <.001   .009 
Completely/very satisfied 39 (38.2%) 63 (61.8%)  — —  
Moderately/slightly/not satisfied 63 (67.7%) 30 (32.3%)  2.43 1.25-4.78  
Social support score   <.001   .13 
Greater than median (higher levels of support) 40 (40.0%) 60 (60.0%)  — —  
Less than or equal to median (lower levels of support) 64 (64.6%) 35 (35.4%)  1.69 0.86-3.30  
Chemotherapy started before study consent   .85    
Yes 38 (50.7%) 37 (49.3%)     
No 64 (52.0%) 59 (48.0%)     
Medical mistrust score   .001   .025 
Greater than median (lower levels of mistrust) 34 (39.1%) 53 (60.9%)  — —  
Less than or equal to median (higher levels of mistrust) 70 (62.5%) 42 (37.5%)  2.09 1.10-4.02  
Characteristic UnadjustedAdjusted, n = 192
Anxiety symptoms present (HADS-A ≥ 8)
n = 104
Anxiety symptoms absent (HADS-A < 8)
n = 96
P valueOR95% CIP value
Age group, y   <.001   .010 
≥60 45 (40.5%) 66 (59.5%)  — —  
<60 59 (66.3%) 30 (33.7%)  2.36 1.23-4.59  
Gender identity   .014   .026 
Not female 48 (44.0%) 61 (56.0%)  — —  
Female 56 (61.5%) 35 (38.5%)  2.11 1.09-4.14  
Marital status   .001   .14 
Married/living with partner 67 (45.3%) 81 (54.7%)  — —  
Other 37 (71.2%) 15 (28.8%)  1.78 0.83-3.95  
Highest level of education achieved   .55    
Bachelor degree or higher 64 (50.4%) 63 (49.6%)     
Less than bachelor degree 40 (54.8%) 33 (45.2%)     
Religion/spiritual practice   .18    
Has a religion/spiritual practice 80 (49.7%) 81 (50.3%)     
No religion/spiritual practice 24 (61.5%) 15 (38.5%)     
Race   .87    
White 88 (51.8%) 82 (48.2%)     
Non-White 16 (53.3%) 14 (46.7%)     
Ethnicity   .44    
Not Hispanic or Latinx 97 (51.6%) 91 (48.4%)     
Hispanic or Latinx 7 (63.6%) 4 (36.4%)     
Monthly household income, $   .15    
≥7000 42 (47.7%) 46 (52.3%)     
<7000 57 (58.2%) 41 (41.8%)     
Family finances at end of month    .014    
Some money left over 59 (46.8%) 67 (53.2%)     
Just enough/not enough money left over 42 (65.6%) 22 (34.4%)     
Satisfaction with family finances   <.001   .009 
Completely/very satisfied 39 (38.2%) 63 (61.8%)  — —  
Moderately/slightly/not satisfied 63 (67.7%) 30 (32.3%)  2.43 1.25-4.78  
Social support score   <.001   .13 
Greater than median (higher levels of support) 40 (40.0%) 60 (60.0%)  — —  
Less than or equal to median (lower levels of support) 64 (64.6%) 35 (35.4%)  1.69 0.86-3.30  
Chemotherapy started before study consent   .85    
Yes 38 (50.7%) 37 (49.3%)     
No 64 (52.0%) 59 (48.0%)     
Medical mistrust score   .001   .025 
Greater than median (lower levels of mistrust) 34 (39.1%) 53 (60.9%)  — —  
Less than or equal to median (higher levels of mistrust) 70 (62.5%) 42 (37.5%)  2.09 1.10-4.02  

ORs from multivariable logistic regression; ORs of >1 corresponding to increased odds of having clinically significant anxiety present.

Percentages are row percentages. Frequency counts do not sum to column totals because of missing data as follows: ethnicity (anxiety absent, n = 1); monthly household income (anxiety present, n = 5; anxiety absent, n = 9); family finances at end of month (anxiety present, n = 3; anxiety absent, n = 7); satisfaction with family finances (anxiety present, n = 2; anxiety absent, n = 3); social support score (anxiety absent, n = 1); chemotherapy status at study consent (anxiety present, n = 2); and medical mistrust score (anxiety absent, n = 1).

Only 7 of 64 participants with “just enough” or “not enough money left over” at the end of the month were completely/very satisfied with their family finances. Because of this overlap, “satisfaction with family finances” was included in the multivariable model, whereas “family finances at end of the month” was not included in the model.

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