Table 5.

Correlation between CD4/CD8 ratios and preapheresis factors

UnivariateMultivariate
CoefficientLo_95% CIUp_95% CIP valueCoefficientLo_95% CIUp_95% CIP value
Age at apheresis Per year 0.022 −0.005 0.049 .107     
Sex Female vs male 0.037 −0.380 0.454 .860     
ISS at diagnosis II vs I −0.394 −0.941 0.152 .155 −0.387 −0.906 0.131 .141 
 III vs I −0.708 −1.293 −0.123 .018∗  −0.559 −1.104 −0.013 .045∗  
deletion 17p Yes vs no −0.408 −0.976 0.160 .157     
Disease status at apheresis SD/PD vs CR/PR 0.081 −0.464 0.626 .768     
Time from diagnosis to apheresis Per month 0.000 −0.004 0.004 .885     
Number of prior lines Per line −0.093 −0.176 −0.010 .028∗  −0.056 −0.146 0.034 .223 
Time from last chemotherapy to apheresis Per day −0.001 −0.003 0.001 .596     
History of ASCT Once vs no −0.126 −0.783 0.530 .704     
 ≥2 vs no −0.724 −1.443 −0.005 .048     
Time from last ASCT to apheresis Per month 0.002 −0.003 0.008 .434     
IMiDs in last regimen Yes vs no −0.111 −0.532 0.309 .601     
Time from last IMiDs to apheresis Per month 0.008 −0.013 0.029 .443     
Protease inhibitor in last regimen Yes vs no 0.292 −0.126 0.709 .169     
Anti-CD38 antibodies in last regimen Yes vs no 0.033 −0.382 0.448 .874     
Alkylator in last regimen Yes vs no −0.648 −1.140 −0.157 .010∗      
Prior alkylating agent within 6 months Yes vs no −0.823 −1.254 −0.393 <.001∗  −0.594 −1.101 −0.086 .022∗  
History of RT Yes vs no −0.760 −1.154 −0.367 <.001∗  −0.536 −0.965 −0.108 .015∗  
Total dose of RT Per Gy −0.004 −0.013 0.005 .332     
Time from last RT to apheresis Per month −0.006 −0.017 0.006 .333     
UnivariateMultivariate
CoefficientLo_95% CIUp_95% CIP valueCoefficientLo_95% CIUp_95% CIP value
Age at apheresis Per year 0.022 −0.005 0.049 .107     
Sex Female vs male 0.037 −0.380 0.454 .860     
ISS at diagnosis II vs I −0.394 −0.941 0.152 .155 −0.387 −0.906 0.131 .141 
 III vs I −0.708 −1.293 −0.123 .018∗  −0.559 −1.104 −0.013 .045∗  
deletion 17p Yes vs no −0.408 −0.976 0.160 .157     
Disease status at apheresis SD/PD vs CR/PR 0.081 −0.464 0.626 .768     
Time from diagnosis to apheresis Per month 0.000 −0.004 0.004 .885     
Number of prior lines Per line −0.093 −0.176 −0.010 .028∗  −0.056 −0.146 0.034 .223 
Time from last chemotherapy to apheresis Per day −0.001 −0.003 0.001 .596     
History of ASCT Once vs no −0.126 −0.783 0.530 .704     
 ≥2 vs no −0.724 −1.443 −0.005 .048     
Time from last ASCT to apheresis Per month 0.002 −0.003 0.008 .434     
IMiDs in last regimen Yes vs no −0.111 −0.532 0.309 .601     
Time from last IMiDs to apheresis Per month 0.008 −0.013 0.029 .443     
Protease inhibitor in last regimen Yes vs no 0.292 −0.126 0.709 .169     
Anti-CD38 antibodies in last regimen Yes vs no 0.033 −0.382 0.448 .874     
Alkylator in last regimen Yes vs no −0.648 −1.140 −0.157 .010∗      
Prior alkylating agent within 6 months Yes vs no −0.823 −1.254 −0.393 <.001∗  −0.594 −1.101 −0.086 .022∗  
History of RT Yes vs no −0.760 −1.154 −0.367 <.001∗  −0.536 −0.965 −0.108 .015∗  
Total dose of RT Per Gy −0.004 −0.013 0.005 .332     
Time from last RT to apheresis Per month −0.006 −0.017 0.006 .333     

Abbreviations are explained in Table 4.

∗

indicates P < .05.

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