Correlation between platelet counts and preapheresis factors
| . | . | Univariate . | Multivariate . | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Coefficient . | Lo_95% CI . | Up_95% CI . | P value . | Coefficient . | Lo_95% CI . | Up_95% CI . | P value . | ||
| Age at apheresis | Per year | 0.425 | −1.582 | 2.432 | .676 | ||||
| Sex | Female vs male | 17.604 | −13.563 | 48.770 | .266 | ||||
| ISS at diagnosis | II vs I | 13.569 | −27.975 | 55.112 | .519 | ||||
| III vs I | 9.170 | −34.248 | 52.588 | .677 | |||||
| deletion 17p | Yes vs no | −1.400 | −47.989 | 45.189 | .953 | ||||
| Disease status at apheresis | SD/PD vs CR/PR | 0.920 | −44.581 | 46.421 | .968 | ||||
| Time from diagnosis to apheresis | Per month | 0.032 | −0.228 | 0.291 | .810 | ||||
| Number of prior lines | Per line | −4.892 | −11.484 | 1.700 | .145 | ||||
| Time from last chemotherapy to apheresis | Per day | −0.076 | −0.226 | 0.075 | .322 | ||||
| History of ASCT | Once vs no | −18.285 | −62.695 | 26.126 | .417 | −22.324 | −66.203 | 21.554 | .316 |
| ≥2 vs no | −46.019 | −97.367 | 5.330 | .079 | −43.196 | −93.835 | 7.442 | .094 | |
| Time from last ASCT to apheresis | Per month | −0.009 | −0.425 | 0.408 | .967 | ||||
| IMiDs in last regimen | Yes vs no | −4.102 | −35.344 | 27.140 | .796 | ||||
| Time from last IMiDs to apheresis | Per month | 0.486 | −0.650 | 1.622 | .398 | ||||
| Protease inhibitors in last regimen | Yes vs no | −5.845 | −37.364 | 25.673 | .715 | ||||
| Anti-CD38 antibodies in last regimen | Yes vs no | 10.341 | −20.705 | 41.387 | .512 | ||||
| Alkylator in last regimen | Yes vs no | −35.697 | −75.031 | 3.637 | .075 | ||||
| Prior alkylating agent within 6 months | Yes vs no | −44.055 | −78.784 | −9.326 | .013∗ | −42.073 | −77.144 | −7.003 | .019∗ |
| History of RT | Yes vs no | −2.587 | −34.048 | 28.874 | .871 | ||||
| Total dose of RT | Per Gy | −0.069 | −0.807 | 0.669 | .852 | ||||
| Time from last RT to apheresis | Per month | −0.147 | −0.993 | 0.699 | .728 | ||||
| . | . | Univariate . | Multivariate . | ||||||
|---|---|---|---|---|---|---|---|---|---|
| Coefficient . | Lo_95% CI . | Up_95% CI . | P value . | Coefficient . | Lo_95% CI . | Up_95% CI . | P value . | ||
| Age at apheresis | Per year | 0.425 | −1.582 | 2.432 | .676 | ||||
| Sex | Female vs male | 17.604 | −13.563 | 48.770 | .266 | ||||
| ISS at diagnosis | II vs I | 13.569 | −27.975 | 55.112 | .519 | ||||
| III vs I | 9.170 | −34.248 | 52.588 | .677 | |||||
| deletion 17p | Yes vs no | −1.400 | −47.989 | 45.189 | .953 | ||||
| Disease status at apheresis | SD/PD vs CR/PR | 0.920 | −44.581 | 46.421 | .968 | ||||
| Time from diagnosis to apheresis | Per month | 0.032 | −0.228 | 0.291 | .810 | ||||
| Number of prior lines | Per line | −4.892 | −11.484 | 1.700 | .145 | ||||
| Time from last chemotherapy to apheresis | Per day | −0.076 | −0.226 | 0.075 | .322 | ||||
| History of ASCT | Once vs no | −18.285 | −62.695 | 26.126 | .417 | −22.324 | −66.203 | 21.554 | .316 |
| ≥2 vs no | −46.019 | −97.367 | 5.330 | .079 | −43.196 | −93.835 | 7.442 | .094 | |
| Time from last ASCT to apheresis | Per month | −0.009 | −0.425 | 0.408 | .967 | ||||
| IMiDs in last regimen | Yes vs no | −4.102 | −35.344 | 27.140 | .796 | ||||
| Time from last IMiDs to apheresis | Per month | 0.486 | −0.650 | 1.622 | .398 | ||||
| Protease inhibitors in last regimen | Yes vs no | −5.845 | −37.364 | 25.673 | .715 | ||||
| Anti-CD38 antibodies in last regimen | Yes vs no | 10.341 | −20.705 | 41.387 | .512 | ||||
| Alkylator in last regimen | Yes vs no | −35.697 | −75.031 | 3.637 | .075 | ||||
| Prior alkylating agent within 6 months | Yes vs no | −44.055 | −78.784 | −9.326 | .013∗ | −42.073 | −77.144 | −7.003 | .019∗ |
| History of RT | Yes vs no | −2.587 | −34.048 | 28.874 | .871 | ||||
| Total dose of RT | Per Gy | −0.069 | −0.807 | 0.669 | .852 | ||||
| Time from last RT to apheresis | Per month | −0.147 | −0.993 | 0.699 | .728 | ||||
ASCT, autologous stem cell transplantation; IMiDs, immunomodulatory drugs; Lo, lower limit; RT, radiation therapy; Up, upper limit.
indicates P < .05.