Transplant characteristics
. | ICIs . | No-ICIs . | P value . |
---|---|---|---|
Donor type, n (%) | P < .001 | ||
HLA haploidentical | 48 (68%) | 70 (92%) | |
HLA matched | 7 (10%) | 2 (3%) | |
HLA mismatched | 16 (22%) | 4 (5%) | |
Median donor age, (IQR), y | 28 (23-38) | 41 (26-54) | P < .001 |
Allograft source, n (%) | P = .03 | ||
Bone marrow | 53 (75%) | 69 (91%) | |
Peripheral blood | 17 (24%) | 6 (8%) | |
Cord blood | 1 (1%) | 1 (1%) | |
Count recovery time, median (range), d | |||
Days to neutrophil count recovery | 17 (12-54) | 16 (7-64) | P = .21 |
Days to platelet count recovery | 25 (11-133) | 24 (11-79) | P = .04 |
Engraftment/chimerism at day +60 | P = .005 | ||
Full donor chimerism (<5% patient) | 43 (60.5%) | 64 (84.2%) | |
Mixed chimerism (5%-94% patient) | 16 (22.5%) | 8 (10.5%) | |
Graft failure | 12 (16.9%) | 4 (5.3%) |
. | ICIs . | No-ICIs . | P value . |
---|---|---|---|
Donor type, n (%) | P < .001 | ||
HLA haploidentical | 48 (68%) | 70 (92%) | |
HLA matched | 7 (10%) | 2 (3%) | |
HLA mismatched | 16 (22%) | 4 (5%) | |
Median donor age, (IQR), y | 28 (23-38) | 41 (26-54) | P < .001 |
Allograft source, n (%) | P = .03 | ||
Bone marrow | 53 (75%) | 69 (91%) | |
Peripheral blood | 17 (24%) | 6 (8%) | |
Cord blood | 1 (1%) | 1 (1%) | |
Count recovery time, median (range), d | |||
Days to neutrophil count recovery | 17 (12-54) | 16 (7-64) | P = .21 |
Days to platelet count recovery | 25 (11-133) | 24 (11-79) | P = .04 |
Engraftment/chimerism at day +60 | P = .005 | ||
Full donor chimerism (<5% patient) | 43 (60.5%) | 64 (84.2%) | |
Mixed chimerism (5%-94% patient) | 16 (22.5%) | 8 (10.5%) | |
Graft failure | 12 (16.9%) | 4 (5.3%) |
IQR, interquartile range.