Table 3.

Univariate and multivariate survival analysis

VariableUnivariateMultivariate
HR (95% CI)P valueHR (95% CI)P value
Overall cohort     
Age 1.05 (1.04-1.06) <.001 1.04 (1.02-1.05) <.001 
R-ISS III 2.4 (1.7-3.2) <.001 2.1 (1.4-3.1) <.001 
Early transplantation 0.5 (0.3-0.6) <.001 0.7 (0.5-1.0) .04 
≥VGPR 0.6 (0.5-0.8) <.001 0.6 (0.5-0.8) <.001 
Frail 1.8 (1.4-2.3) <.001 1.5 (1.1-2.1) .008 
Relationship status married/relationship status vs no 0.6 (0.4-0.8) .001 1.6 (1.1-2.4) .01 
SES, Q4 vs Q1-Q3 0.7 (0.5-0.9) .02 0.8 (0.6-1.1) .13 
Age ≥60 y     
Age 1.07 (1.05-1.08) <.001 1.03 (1.01-1.06) .01 
R-ISS III 3.7 (2.6-5.3) <.001 2.6 (1.6--4.0) <.001 
Early transplantation 0.3 (0.2-0.5) <.001 0.6 (0.4-0.9) .03 
≥VGPR 0.6 (0.4-0.8) <.001 0.6 (0.4-0.9) .01 
Frail 1.8 (1.4-2.4) <.001 1.6 (1.1-2.4) .008 
Relationship status married/relationship status vs no 0.5 (0.4-0.7) <.001 0.7 (0.5-1.1) .17 
SES, Q4 vs Q1-Q3 0 (0.5-0.9) .003 0.8 (0.6-1.2) .32 
VariableUnivariateMultivariate
HR (95% CI)P valueHR (95% CI)P value
Overall cohort     
Age 1.05 (1.04-1.06) <.001 1.04 (1.02-1.05) <.001 
R-ISS III 2.4 (1.7-3.2) <.001 2.1 (1.4-3.1) <.001 
Early transplantation 0.5 (0.3-0.6) <.001 0.7 (0.5-1.0) .04 
≥VGPR 0.6 (0.5-0.8) <.001 0.6 (0.5-0.8) <.001 
Frail 1.8 (1.4-2.3) <.001 1.5 (1.1-2.1) .008 
Relationship status married/relationship status vs no 0.6 (0.4-0.8) .001 1.6 (1.1-2.4) .01 
SES, Q4 vs Q1-Q3 0.7 (0.5-0.9) .02 0.8 (0.6-1.1) .13 
Age ≥60 y     
Age 1.07 (1.05-1.08) <.001 1.03 (1.01-1.06) .01 
R-ISS III 3.7 (2.6-5.3) <.001 2.6 (1.6--4.0) <.001 
Early transplantation 0.3 (0.2-0.5) <.001 0.6 (0.4-0.9) .03 
≥VGPR 0.6 (0.4-0.8) <.001 0.6 (0.4-0.9) .01 
Frail 1.8 (1.4-2.4) <.001 1.6 (1.1-2.4) .008 
Relationship status married/relationship status vs no 0.5 (0.4-0.7) <.001 0.7 (0.5-1.1) .17 
SES, Q4 vs Q1-Q3 0 (0.5-0.9) .003 0.8 (0.6-1.2) .32 
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