Table 5.

Outcomes of patients who responded to bridging therapy

Response to bridgingPatient numberSystemic responseCNS responsePFS, moOS, mo
CR Patient 10 CR (day 30) Yes (day 30) 9.7 12.1 
VGPR Patient 7 VGPR (day 30) sCR (6 mo) Yes (day 30) 6.3 13.3 
PR Patient 8 VGPR (day 30) sCR (6 mo) Yes (day 30) 33.4 
PR Patient 2 CR (day 30) Yes (day 90)  6.3  6.3  
Response to bridgingPatient numberSystemic responseCNS responsePFS, moOS, mo
CR Patient 10 CR (day 30) Yes (day 30) 9.7 12.1 
VGPR Patient 7 VGPR (day 30) sCR (6 mo) Yes (day 30) 6.3 13.3 
PR Patient 8 VGPR (day 30) sCR (6 mo) Yes (day 30) 33.4 
PR Patient 2 CR (day 30) Yes (day 90)  6.3  6.3  

First CNS response assessment after CAR T-cell therapy was done at day 90, with no available data at day 30.

Patient achieved CR but died without progression at 6.3 months due to fatal sepsis.

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