Table 2. Univariable and multivariable... | American Society of Hematology

Table 2.

Univariable and multivariable analysis for RFS

Characteristic	Univariable					Multivariable
Characteristic	N	Event, n	HR	95% CI	P value	HR	95% CI	P value
Age, y	277	140
<60			Ref			Ref
≥60			1.82	1.24-2.65	<.01	1.17	0.77-1.77	.45
ELN 2022	277	140
Favorable			Ref			Ref
Intermediate			1.30	0.74-2.28	.36	0.98	0.50-1.90	.95
Adverse (non-complex, TP53^WT)			1.35	0.70-2.60	.37	1.00	0.50-2.02	1.00
Adverse (complex and/or TP53^mut)			2.81	1.54-5.14	<.01	2.58	1.34-4.98	<.01
Treatment	277	140
IC			Ref			Ref
IC+VEN			0.37	0.20-0.71	<.01	0.47	0.24-0.90	.02
MRD status	277	140
Neg/Neg			Ref			Ref
Pos/Neg			1.56	0.98-2.46	.058	1.73	1.09-2.75	.02
Pos/Pos			3.65	2.46-5.40	<.01	3.67	2.35-5.76	<.01
SCT in first remission	277	140	0.46	0.32-0.66	<.01	0.41	0.28-0.60	<.01

Characteristic	Univariable					Multivariable
Characteristic	N	Event, n	HR	95% CI	P value	HR	95% CI	P value
Age, y	277	140
<60			Ref			Ref
≥60			1.82	1.24-2.65	<.01	1.17	0.77-1.77	.45
ELN 2022	277	140
Favorable			Ref			Ref
Intermediate			1.30	0.74-2.28	.36	0.98	0.50-1.90	.95
Adverse (non-complex, TP53^WT)			1.35	0.70-2.60	.37	1.00	0.50-2.02	1.00
Adverse (complex and/or TP53^mut)			2.81	1.54-5.14	<.01	2.58	1.34-4.98	<.01
Treatment	277	140
IC			Ref			Ref
IC+VEN			0.37	0.20-0.71	<.01	0.47	0.24-0.90	.02
MRD status	277	140
Neg/Neg			Ref			Ref
Pos/Neg			1.56	0.98-2.46	.058	1.73	1.09-2.75	.02
Pos/Pos			3.65	2.46-5.40	<.01	3.67	2.35-5.76	<.01
SCT in first remission	277	140	0.46	0.32-0.66	<.01	0.41	0.28-0.60	<.01

Ref, reference; TP53^mut, mutated TP53; TP53^WT, wildtype TP53.

Boldface indicates P values < 0.05 are considered significant.